Living with sulfonamides: a diverse range of mechanisms observed in bacteria

OC Nunes, CM Manaia, BA Kolvenbach… - Applied microbiology …, 2020 - Springer
Sulfonamides are the oldest class of synthetic antibiotics still in use in clinical and veterinary
settings. The intensive utilization of sulfonamides has been leading to the widespread …

The complex Interplay between antibiotic resistance and pharmaceutical and personal care products in the environment

CM Manaia, DS Aga, E Cytryn, WH Gaze… - Environmental …, 2024 - Wiley Online Library
Antibiotic‐resistant bacteria (ARB) and antibiotic resistance genes (ARGs) are important
environmental contaminants. Nonetheless, what drives the evolution, spread, and …

[HTML][HTML] Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national …

MJ Wade, AL Jacomo, E Armenise, MR Brown… - Journal of hazardous …, 2022 - Elsevier
The COVID-19 pandemic has put unprecedented pressure on public health resources
around the world. From adversity, opportunities have arisen to measure the state and …

Using sewage for surveillance of antimicrobial resistance

FM Aarestrup, MEJ Woolhouse - Science, 2020 - science.org
Antimicrobial resistance (AMR), a cross-cutting and increasing threat to global health (1–3),
is a complex problem with multiple and interconnected drivers. Reliable surveillance data …

Predicting antibiotic resistance gene abundance in activated sludge using shotgun metagenomics and machine learning

Y Sun, B Clarke, J Clarke, X Li - Water Research, 2021 - Elsevier
While the microbiome of activated sludge (AS) in wastewater treatment plants (WWTPs)
plays a vital role in shaping the resistome, identifying the potential bacterial hosts of …

[HTML][HTML] A global multinational survey of cefotaxime-resistant coliforms in urban wastewater treatment plants

RBM Marano, T Fernandes, CM Manaia, O Nunes… - Environment …, 2020 - Elsevier
Abstract The World Health Organization Global Action Plan recommends integrated
surveillance programs as crucial strategies for monitoring antibiotic resistance. Although …

Metagenomic insight into microbiome and antibiotic resistance genes of high clinical concern in urban and rural hospital wastewater of northern India origin: a major …

A Talat, KS Blake, G Dantas, AU Khan - Microbiology spectrum, 2023 - Am Soc Microbiol
India is one of the largest consumers and producers of antibiotics and a hot spot for the
emergence and proliferation of antimicrobial resistance genes (ARGs). Indian hospital …

Metagenomic surveillance of antibiotic resistome in influent and effluent of wastewater treatment plants located on the Qinghai-Tibetan Plateau

B Shi, R Zhao, G Su, B Liu, W Liu, J Xu, Q Li… - Science of The Total …, 2023 - Elsevier
As hotspots for the dissemination of antibiotic resistance genes (ARGs), wastewater
treatment plants (WWTPs) have attracted global attention. However, there lacks a sufficient …

Application of high-throughput sequencing technologies and analytical tools for pathogen detection in urban water systems: Progress and future perspectives

Y Zhao, F Huang, W Wang, R Gao, L Fan… - Science of the Total …, 2023 - Elsevier
The ubiquitous presence of pathogenic microorganisms, such as viruses, bacteria, fungi,
and protozoa, in urban water systems poses a significant risk to public health. The …

Standard sample storage conditions have an impact on inferred microbiome composition and antimicrobial resistance patterns

CS Poulsen, RS Kaas, FM Aarestrup… - Microbiology …, 2021 - Am Soc Microbiol
Storage of biological specimens is crucial in the life and medical sciences. Storage
conditions for samples can be different for a number of reasons, and it is unclear what effect …