Using conditional independence tests to elucidate causal links in cell cycle regulation in Escherichia coli

P Kar, S Tiruvadi-Krishnan, J Männik… - Proceedings of the …, 2023 - National Acad Sciences
How cells regulate their cell cycles is a central question for cell biology. Models of cell size
homeostasis have been proposed for bacteria, archaea, yeast, plant, and mammalian cells …

Quantitative Examination of Five Stochastic Cell-Cycle and Cell-Size Control Models for Escherichia coli and Bacillus subtilis

G Le Treut, F Si, D Li, S Jun - Frontiers in microbiology, 2021 - frontiersin.org
We examine five quantitative models of the cell-cycle and cell-size control in Escherichia coli
and Bacillus subtilis that have been proposed over the last decade to explain single-cell …

Response to comment on 'Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism'

G Witz, T Julou, E van Nimwegen - bioRxiv, 2020 - biorxiv.org
Last year we published an article in which we used time-lapse microscopy in combination
with microfluidics to measure growth, division and replication in single E. coli cells on the …

Noise signature in added size suggests bacteria target a commitment size to enable division

C Nieto, J Arias-Castro, C Vargas-García, C Sánchez… - bioRxiv, 2020 - biorxiv.org
Recent experiments suggested that sizer-like division strategy, a deviation from the adder
paradigm might be produced by additional degradation events of cell division machinery …

Single Cell Growth and Division Models

P Kar - 2024 - search.proquest.com
Cells coordinate their growth and division to maintain a finite size. They undertake important
processes within a cell cycle such as DNA replication. How these processes such as cell …

Single-cell data and correlation analysis support the independent double adder model in both Escherichia coli and Bacillus subtilis

G Le Treut, F Si, D Li, S Jun - bioRxiv, 2020 - biorxiv.org
The reference point for cell-size control in the cell cycle is a fundamental biological question.
We previously reported that we were unable to reproduce the conclusions of Witz et al.'s …