Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Background There is a lack of consensus about the effect of the COVID-19 pandemic on the
mental health of children and adolescents. We aimed to compare rates of paediatric …

Objective To assess the associations between statins and adverse events in primary
prevention of cardiovascular disease and to examine how the associations vary by type and …

Uno de los principales problemas de la investigación clínica radica en la dificultad de
seleccionar el mejor diseño para dar respuesta al problema de investigación, lo cual puede …

Importance There is a growing body of high-quality cohort-based research that has
examined changes in child and adolescent mental health during the COVID-19 pandemic vs …

Objective: Fluid administration in combination with the increase in vasopermeability induced
by critical illness often results in significant fluid overload in critically ill patients. Recent …

Objectives The aim of this study was to develop a critical appraisal (CA) tool that addressed
study design and reporting quality as well as the risk of bias in cross-sectional studies …

Abstract Randomized Controlled Trials (RCTs) are increasingly popular in the social
sciences, not only in medicine. We argue that the lay public, and sometimes researchers, put …

There are two common misconceptions about case-control studies: that matching in itself
eliminates (controls) confounding by the matching factors, and that if matching has been …

The clinical course of cirrhosis is mostly determined by the progressive increase of portal
hypertension, hyperdynamic circulation, bacterial translocation and activation of systemic …