DYRK1A: a down syndrome-related dual protein kinase with a versatile role in tumorigenesis
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a dual kinase
that can phosphorylate its own activation loop on tyrosine residue and phosphorylate its …
that can phosphorylate its own activation loop on tyrosine residue and phosphorylate its …
Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: A combinational approach for enhanced delivery of nanoparticles
Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …
A review on the assessment of imidazo [1, 2-a] pyridines as corrosion inhibitor of metals
Abstract Imidazo [1, 2-a] pyridines find great importance in several commercially available
drugs but recently, this derivative has been reported as effective corrosion inhibitors due to …
drugs but recently, this derivative has been reported as effective corrosion inhibitors due to …
Molecular characterization of the grape seeds extract's effect against chemically induced liver cancer: In vivo and in vitro analyses
The purpose of this study was to investigate the anti-cancer property of grape seed extract
(GSE) during early stages of developing liver cancer using a two-stage carcinogenic model …
(GSE) during early stages of developing liver cancer using a two-stage carcinogenic model …
Enhanced drug delivery using sonoactivatable liposomes with membrane-embedded porphyrins
X Wang, F Yan, X Liu, P Wang, S Shao, Y Sun… - Journal of controlled …, 2018 - Elsevier
Small molecules that interfere with nucleic acid are widely used in chemotherapy, however,
improved delivery approaches are required to improve anti-tumor outcomes. Here, we …
improved delivery approaches are required to improve anti-tumor outcomes. Here, we …
Upregulation of Akt/NF-κB-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic …
B Tang, F Tang, Z Wang, G Qi, X Liang… - International Journal …, 2016 - Taylor & Francis
Primary liver cancer is globally the sixth most frequent cancer, and the second leading
cause of cancer death and its incidence is increasing in many countries, becoming a serious …
cause of cancer death and its incidence is increasing in many countries, becoming a serious …
Monitoring doxorubicin cellular uptake and trafficking using in vitro Raman microspectroscopy: short and long time exposure effects on lung cancer cell lines
Z Farhane, F Bonnier, HJ Byrne - Analytical and bioanalytical chemistry, 2017 - Springer
Raman microspectroscopy is a non-invasive, in vitro analytical tool which is being
increasingly explored for its potential in clinical applications and monitoring the uptake …
increasingly explored for its potential in clinical applications and monitoring the uptake …
Selenylated Imidazo[1,2-a]pyridine Induces Cell Senescence and Oxidative Stress in Chronic Myeloid Leukemia Cells
GT Burkner, DA Dias, KFS Souza, AJP Araújo… - Molecules, 2023 - mdpi.com
Imidazo [1, 2-a] pyridines (IPs) have been studied regarding drug development. The
objective of this work was to evaluate the antileukemic capacity of IP derivatives by …
objective of this work was to evaluate the antileukemic capacity of IP derivatives by …
Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro‐spectroscopy: binding signatures, drug resistance and DNA repair
Z Farhane, F Bonnier, O Howe, A Casey… - Journal of …, 2018 - Wiley Online Library
Raman micro‐spectroscopy is a non‐invasive analytical tool, whose potential in cellular
analysis and monitoring drug mechanisms of action has already been demonstrated, and …
analysis and monitoring drug mechanisms of action has already been demonstrated, and …
Novel selenylated imidazo [1, 2-a] pyridines for breast cancer chemotherapy: Inhibition of cell proliferation by Akt-mediated regulation, DNA cleavage and apoptosis
A novel series of selenylated imidazo [1, 2-a] pyridines were designed and synthesized with
a view to a promising activity against breast cancer cell. The compounds, 7-methyl-3 …
a view to a promising activity against breast cancer cell. The compounds, 7-methyl-3 …