In the past few decades, biosensors have been gradually developed for the rapid detection
and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have …

Nucleic acid aptamers are single-stranded DNA or RNA molecules selected in vitro that can
bind to a broad range of targets with high affinity and specificity. As promising alternatives to …

Abstract Hemoglobin (Hb) and myoglobin (Mb) are kinds of heme-binding proteins that play
crucial physiological roles in different organisms. With rapid application development in food …

DNA–protein complexes are attractive components with broad applications in various
research fields, such as DNA aptamer–enzyme complexes as biosensing elements …

Although biosensors for signal monitoring have been extensively developed, their
application in one-step high-throughput detection of low-abundance disease biomarkers …

Abstract Background G-quadruplex (G4)/hemin DNAzymes with conversion of substrates
into colorimetric readouts are well recognized as convenient biocatalysis tools in sensor …

p53 gene is one of the most important anticancer genes and has been recognized as a
typical biomarker for the early diagnosis of cancers. In this paper, a portable point-of-care …

Aptamer modification especially for pharmacotherapeutic applications is very important for
serum and endo/exonuclease stability. Although alterations in aptamer structure such as …

The insufficient internal resorption of iodide ions (I−) leads to thyroid disorders, such as
goiter, hypothyroidism, and cretinism in adults. In this paper, a portable point-of-care testing …

Aptamers, synthetic oligonucleotide ligands, have shown significant promise for therapeutic
and diagnostic applications owing to their high specificity and affinity for target molecules …