Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

In adult mammals, blood cells are formed from hematopoietic stem progenitor cells, which
are controlled by a complex cellular microenvironment called “niche”. Drosophila …

During the past 60 years, the fruit fly, Drosophila melanogaster, has proven to be an
excellent model to study the regulation of hematopoiesis. This is not only due to the …

Mechanistic studies of Drosophila lymph gland hematopoiesis are limited by the availability
of cell-type-specific markers. Using a combination of bulk RNA-Seq of FACS-sorted cells …

Stem cells typically reside in a specialized physical and biochemical environment that
facilitates regulation of their behavior. For this reason, stem cells are ideally studied in …

Notch signaling is a highly conserved pathway between mammals and Drosophila and
plays a key role in various biological processes. Drosophila has emerged as a powerful …

Transdifferentiation is a conversion of an already differentiated cell type into another cell
type without the involvement of stem cells. This transition is well described in the case of …

In Drosophila, definitive haematopoiesis takes place in a specialized organ termed “lymph
gland”. It harbours multi‐potent stem‐like blood progenitor cells whose development …

The Drosophila hematopoietic system is becoming increasingly attractive for its simple blood
cell lineage and its developmental and functional parallels with the vertebrate system. As the …

Notch signalling activity regulates hematopoiesis in Drosophila and vertebrates alike.
Parasitoid wasp infestation of Drosophila larvae, however, requires a timely downregulation …