The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …

BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …

Aim The current study investigated the impact of maternal obesity on placental phenotype in
relation to fetal growth and sex. Methods Female C57BL6/J mice were fed either a diet high …

Key points Inappropriate intake of key micronutrients in pregnancy is known to alter maternal
endocrine status, impair placental development and induce fetal growth restriction …

Poor environmental conditions, including malnutrition, hypoxia and obesity in the mother
increase the risk of pregnancy complications, such as pre-eclampsia and gestational …

Key points Mitochondrial dysfunction is known to occur in diabetic phenotypes including
type 1 and 2 diabetes mellitus. The incidence of gestational diabetes mellitus (GDM) is …

Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with d-
glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial …

Glucose metabolism is vital to the survival of living organisms. Since the discovery of the
Warburg effect in the 1920s, glycolysis has become a major research area in the field of …