Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction

S Kant, D Banerjee, SA Sabe, F Sellke, J Feng - Frontiers in Medicine, 2023 - frontiersin.org
Despite significant advances in surgical technique and strategies for tissue/organ protection,
cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human …

The correlation between bowel complications and cardiac surgery

V Mishra, S Hewage, S Islam… - Scandinavian Journal of …, 2021 - journals.sagepub.com
Although advances in knowledge and technology have improved outcomes in surgical
cardiac patients over the last decade, complications following cardiac operations still remain …

Perspective on cerebral microemboli in cardiac surgery: significant problem or much ado about nothing?

SJ Mitchell, AF Merry - The Journal of ExtraCorporeal …, 2015 - ject.edpsciences.org
From the time an association was perceived between cardiac surgery and post-operative
cognitive dysfunction (POCD), there has been interest in arterial microemboli as one …

Overcoming challenges in the management of critical events during cardiopulmonary bypass

J Mukherji, RR Hood… - Seminars in cardiothoracic …, 2014 - journals.sagepub.com
Critical events during cardiopulmonary bypass (CPB) can challenge the most experienced
perfusionists, anesthesiologists, and surgeons and can potentially lead to devastating …

Intraoperative oxygen practices in cardiac surgery: A national survey

A Calhoun, A Pannu, AL Mueller, O Elmadhoun… - Journal of cardiothoracic …, 2022 - Elsevier
Objective To describe the current nationwide perspectives and practice regarding
intraoperative oxygen titration in cardiac surgery. Design Prospective, observational survey …

Hypobaric type oxygenators–physics and physiology

P Chotimol, W Lansdowne, D Machin, K Binas… - …, 2024 - journals.sagepub.com
Brain injury is still a serious complication after cardiac surgery. Gaseous microemboli (GME)
are known to contribute to both short and longer-term brain injury after cardiac surgery …

Con: hyperoxia should not be used routinely in the management of cardiopulmonary bypass

SM Roberts, TJ Cios - Journal of cardiothoracic and vascular …, 2019 - jcvaonline.com
STANDARD ANESTHESIA PRACTICE has traditionally included administering 100%
oxygen before both induction and emergence. Historically, it was not uncommon to deliver …

Quantification of postmembrane gaseous microembolization during venoarterial extracorporeal membrane oxygenation

Y Jiao, KE Gipson, P Bonde, A Mangi, R Hagberg… - ASAIO …, 2018 - journals.lww.com
Prolonged use of venoarterial extracorporeal membrane oxygenation (VA ECMO) may be
complicated by end-organ dysfunction. Although gaseous microemboli (GME) are thought to …

In vitro elimination of gaseous microemboli utilizing hypobaric oxygenation in the Terumo® FX15 oxygenator

S Clingan, M Schuldes, S Francis, H Hoerr Jr… - …, 2016 - journals.sagepub.com
Background: This study examines the efficacy of hypobaric oxygenation as it relates to the
elimination of gaseous microemboli (GME) at designated flow, pressure and temperature …

[PDF][PDF] Effects of air embolism size and location on porcine hepatic microcirculation in machine perfusion

ML Izamis, A Efstathiades, C Keravnou… - Liver …, 2014 - Wiley Online Library
The handling of donor organs frequently introduces air into the microvasculature, but little is
known about the extent of the damage caused as a function of the embolism size and …