The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …

Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic …

Since our proposal of a dualistic model of epithelial ovarian carcinogenesis more than a
decade ago, a large number of molecular and histopathologic studies were published that …

Chromatin remodeling is an essential cellular process for organizing chromatin structure into
either open or close configuration at specific chromatin locations by orchestrating and …

Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Ovarian clear cell (OCCC) and endometrioid (EnOC) carcinomas are often subsumed under
the umbrella term “endometriosis-associated ovarian cancer”(EAOC), since they frequently …

ARID1A has emerged as a tumor suppressor gene, which is mutated in a broad spectrum of
cancers, especially in those arising from ectopic or eutopic endometrium. As a subunit of …

Purpose Despite long and intensive research, endometriosis remains one of the leading
causes of morbidity among premenopausal women. The majority of endometriosis-related …

The AT-rich interacting domain‑containing protein 1A gene (ARID1A) encodes ARID1A, a
member of the SWI/SNF chromatin remodeling complex. Mutation of ARID1A induces …