Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …

Designing spatial and temporal control of vaccine responses

GA Roth, VCTM Picece, BS Ou, W Luo… - Nature Reviews …, 2022 - nature.com
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

pH-responsive polymer nanomaterials for tumor therapy

S Chu, X Shi, Y Tian, F Gao - Frontiers in oncology, 2022 - frontiersin.org
The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Particle toxicology and health-where are we?

M Riediker, D Zink, W Kreyling, G Oberdörster… - Particle and fibre …, 2019 - Springer
Background Particles and fibres affect human health as a function of their properties such as
chemical composition, size and shape but also depending on complex interactions in an …

Recent advances in polymeric nanoparticle-encapsulated drugs against intracellular infections

A Sánchez, SP Mejía, J Orozco - Molecules, 2020 - mdpi.com
Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat
intracellular infections. They have outstanding performance in delivering antimicrobials …

Mechanisms of immune response to inorganic nanoparticles and their degradation products

R Mohammapdour, H Ghandehari - Advanced drug delivery reviews, 2022 - Elsevier
Careful assessment of the biological fate and immune response of inorganic nanoparticles
is crucial for use of such carriers in drug delivery and other biomedical applications. Many …

Exploiting the role of nanoparticles for use in hydrogel-based bioprinting applications: Concept, design, and recent advances

A Chakraborty, A Roy, SP Ravi, A Paul - Biomaterials Science, 2021 - pubs.rsc.org
Three-dimensional (3D) bioprinting is an emerging tissue engineering approach that aims to
develop cell or biomolecule-laden, complex polymeric scaffolds with high precision, using …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

Nano-bio interactions: a neutrophil-centric view

S Keshavan, P Calligari, L Stella, L Fusco… - Cell Death & …, 2019 - nature.com
Neutrophils are key components of the innate arm of the immune system and represent the
frontline of host defense against intruding pathogens. However, neutrophils can also cause …