Canine leishmaniasis: Update on epidemiology, diagnosis, treatment, and prevention

M Morales-Yuste, J Martín-Sánchez… - Veterinary Sciences, 2022 - mdpi.com
Simple Summary Dogs are the main host of Leishmania infantum, a parasite that causes an
incurable disease called canine leishmaniasis. This parasite is transmitted through the bite …

Humoral and cellular immune response in asymptomatic dogs with visceral leishmaniasis: A review

A García-Castro, A Egui, MC Thomas, MC López - Vaccines, 2022 - mdpi.com
Visceral leishmaniasis is one of the deadliest parasitic diseases in the world and affects both
humans and dogs. The host immune response to Leishmania infection plays a critical role in …

Modulation of Host Immune Response during Leishmania infantum Natural Infection: A Whole-Transcriptome Analysis of the Popliteal Lymph Nodes in Dogs

CR Sanz, G Miró, N Sevane… - Frontiers in …, 2022 - frontiersin.org
Leishmania infantum, the etiological agent of canine leishmaniosis (CanL) in Europe, was
responsible of the largest outbreak of human leishmaniosis in Spain. The parasite infects …

Effect of domperidone (leisguard®) on antibody titers, inflammatory markers and creatinine in dogs with leishmaniosis and chronic kidney disease

MA Cavalera, F Gernone, A Uva, P D'Ippolito… - Parasites & vectors, 2021 - Springer
Background Immunotherapeutic drugs, such as domperidone, have been shown to be
promising treatments against canine leishmaniosis (CanL), but limited data are available …

Effective immuno-therapeutic treatment of Canine Leishmaniasis

RAN Ramos, A Giannelli, F Fasquelle… - PLoS Neglected …, 2023 - journals.plos.org
Background Canine Leishmaniasis (CanL) caused by the L. infantum species is one of the
biggest threats to the health of the South American canine population. Chemotherapeutics …

Prognostic factors and life expectancy in canine leishmaniosis

MA Pereira, R Santos, R Oliveira, L Costa, A Prata… - Veterinary …, 2020 - mdpi.com
Canine leishmaniosis (CanL) is a chronic and potentially fatal disease. The prognosis of
CanL depends on the severity of the clinical signs and clinicopathological abnormalities …

Transmission-Blocking Vaccines for Canine Visceral Leishmaniasis: New Progress and Yet New Challenges

JC Leite, AAM Gonçalves, DS De Oliveira, LA Resende… - Vaccines, 2023 - mdpi.com
Dogs with visceral leishmaniasis play a key role in the transmission cycle of Leishmania
infantum to humans in the urban environment. There is a consensus regarding the …

Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis

T Pacheco-Fernandez, G Volpedo… - Biochemical Society …, 2021 - portlandpress.com
Leishmaniasis is a vector-borne Neglected Tropical Disease (NTD) transmitted by the sand
fly and is a major public health problem worldwide. Infections caused by Leishmania …

Vaccine approaches applied to controlling dog ticks

HS Ribeiro, DFS Pereira, O Melo-Junior… - Ticks and Tick-borne …, 2021 - Elsevier
Ticks are considered the most important vectors in veterinary medicine with a profound
impact on animal health worldwide, as well as being key vectors of diseases affecting …

Serodiagnosis of canine leishmaniasis using a novel recombinant chimeric protein constructed with distinct B-cell epitopes from antigenic Leishmania infantum …

DL Vale, DP Lage, AS Machado, CS Freitas… - Veterinary …, 2021 - Elsevier
Visceral leishmaniasis (VL) is an important public health problem in the world, and control
measures are insufficient to avoid the spread of this neglected disease. Dogs are important …