Endoplasmic reticulum (ER) chaperones (eg, calreticulin, heat shock proteins, and
isomerases) perform a multitude of functions within the ER. However, many of these …

Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a
neglected sickness that affects around 6–8 million people worldwide. Originally, CD was …

Background: Molecules secreted by Trypanosoma cruzi (T. cruzi) have beneficial effects on
the immune system and can fight against cancer by inhibiting the growth of tumor cells …

Parasites and cancers have some common antigens. Much scientific evidence in the human
population, animal models, and in vitro experiments exhibit that parasites have significant …

Trypanosoma cruzi is the protozoan that causes Chagas disease (CD), an endemic
parasitosis in Latin America distributed around the globe. If CD is not treated in acute phase …

Background The present study analyzed whether or not the in vitro cultivation for long
periods of time of pre-isolated Leishmania amazonensis from lesions of chronically infected …

Considering the extensive and widespread impact on individuals, cancer can presently be
categorized as a pandemic. In many instances, the development of tumors has been linked …

Calreticulin from parasites and its vertebrate hosts share~ 50% identity and many of its
functions are equally conserved. However, the existing amino acid differences can affect its …

The immune system may aberrantly silence when against “altered self”, which consequently
may develop into malignancies. With the development of tumor immunology and molecular …

Proteins are the structural, functional and evolutionary units of cells. On their surface,
proteins are shaped into numerous depressions and protrusions that provide unique …