Protein secondary structure prediction: A survey of the state of the art
Protein secondary structure prediction (PSSP) is a fundamental task in protein science and
computational biology, and it can be used to understand protein 3-dimensional (3-D) …
computational biology, and it can be used to understand protein 3-dimensional (3-D) …
Predicting potential side effects of drugs by recommender methods and ensemble learning
Drugs provide help and promise for human health, but they usually come with side effects.
Predicting side effects of drugs is a critical issue for the drug discovery. Although several …
Predicting side effects of drugs is a critical issue for the drug discovery. Although several …
Investigation of machine learning techniques on proteomics: A comprehensive survey
PM Sonsare, C Gunavathi - Progress in biophysics and molecular biology, 2019 - Elsevier
Proteomics is the extensive investigation of proteins which has empowered the recognizable
proof of consistently expanding quantities of protein. Proteins are necessary part of living life …
proof of consistently expanding quantities of protein. Proteins are necessary part of living life …
[HTML][HTML] Distinct USP25 and USP28 oligomerization states regulate deubiquitinating activity
M Gersch, JL Wagstaff, AV Toms, B Graves… - Molecular cell, 2019 - cell.com
The evolutionarily related deubiquitinating enzymes (DUBs) USP25 and USP28 comprise
an identical overall domain architecture but are functionally non-redundant: USP28 …
an identical overall domain architecture but are functionally non-redundant: USP28 …
Structural dynamics of Casein Kinase I (CKI) from malarial parasite Plasmodium falciparum (Isolate 3D7): Insights from theoretical modelling and molecular …
The protein kinases (PKs), belonging to serine/threonine kinase (STKs), are important drug
targets for a wide spectrum of diseases in human. Among protein kinases, the Casein …
targets for a wide spectrum of diseases in human. Among protein kinases, the Casein …
WeFold: a coopetition for protein structure prediction
The protein structure prediction problem continues to elude scientists. Despite the
introduction of many methods, only modest gains were made over the last decade for certain …
introduction of many methods, only modest gains were made over the last decade for certain …
[HTML][HTML] In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine
CCS De Oliveira, GRC Pereira, JYS De Alcantara… - Plos one, 2019 - journals.plos.org
Brain-derived neurotrophic factor (BDNF) plays an important role in neurogenesis and
synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs …
synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs …
[HTML][HTML] Reconstitution and optimisation of the biosynthesis of bacterial sugar pseudaminic acid (Pse5Ac7Ac) enables preparative enzymatic synthesis of CMP …
HS Chidwick, EKP Flack, T Keenan, J Walton… - Scientific Reports, 2021 - nature.com
Pseudaminic acids present on the surface of pathogenic bacteria, including gut pathogens
Campylobacter jejuni and Helicobacter pylori, are postulated to play influential roles in the …
Campylobacter jejuni and Helicobacter pylori, are postulated to play influential roles in the …
dSCOPE: a software to detect sequences critical for liquid–liquid phase separation
Membrane-based cells are the fundamental structural and functional units of organisms,
while evidences demonstrate that liquid–liquid phase separation (LLPS) is associated with …
while evidences demonstrate that liquid–liquid phase separation (LLPS) is associated with …
[HTML][HTML] A membrane-inserted structural model of the yeast mitofusin Fzo1
Mitofusins are large transmembrane GTPases of the dynamin-related protein family, and are
required for the tethering and fusion of mitochondrial outer membranes. Their full-length …
required for the tethering and fusion of mitochondrial outer membranes. Their full-length …