Nano drug delivery systems for antisense oligonucleotides (ASO) therapeutics

T Ramasamy, HB Ruttala, S Munusamy… - Journal of Controlled …, 2022 - Elsevier
Cancer, infectious diseases, and metabolic and hereditary genetic disorders are a global
health burden affecting millions of people, with contemporary treatments offering limited …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Polymeric nanostructured materials for biomedical applications

Z Tang, C He, H Tian, J Ding, BS Hsiao, B Chu… - Progress in Polymer …, 2016 - Elsevier
Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …

Clickable polysaccharides for biomedical applications: a comprehensive review

MK Yazdi, SM Sajadi, F Seidi, N Rabiee… - Progress in polymer …, 2022 - Elsevier
Recent advances in materials science and engineering highlight the importance of
designing sophisticated biomaterials with well-defined architectures and tunable properties …

pH‐Sensitive stimulus‐responsive nanocarriers for targeted delivery of therapeutic agents

M Karimi, M Eslami… - Wiley …, 2016 - Wiley Online Library
In recent years miscellaneous smart micro/nanosystems that respond to various exogenous/
endogenous stimuli including temperature, magnetic/electric field, mechanical force …

Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

W Ou, RK Thapa, L Jiang, ZC Soe, M Gautam… - Journal of Controlled …, 2018 - Elsevier
Immunosuppression in tumor microenvironments induced by regulatory T (Treg) cells is
regarded a critical mechanism of tumor immune escape and poses a major impediment to …

PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution

Z Hussain, S Khan, M Imran, M Sohail… - Drug delivery and …, 2019 - Springer
On account of heterogeneity, intrinsic ability of drug resistance, and the potential to invade to
other parts of the body (malignancy), the development of a rational anticancer regimen is …

Polymer-modified liposomes for drug delivery: from fundamentals to applications

Y Cao, X Dong, X Chen - Pharmaceutics, 2022 - mdpi.com
Liposomes are highly advantageous platforms for drug delivery. To improve the colloidal
stability and avoid rapid uptake by the mononuclear phagocytic system of conventional …

Innovative nano-carriers in anticancer drug delivery-a comprehensive review

P Dong, KP Rakesh, HM Manukumar… - Bioorganic …, 2019 - Elsevier
In the scientific field, nanotechnology has offered multipurpose and designated functional
nanoparticles (NPs) for the development of applications in nano-medicine. This present …