Network biology concepts in complex disease comorbidities

JX Hu, CE Thomas, S Brunak - Nature Reviews Genetics, 2016 - nature.com
The co-occurrence of diseases can inform the underlying network biology of shared and
multifunctional genes and pathways. In addition, comorbidities help to elucidate the effects …

Machine learning models to predict childhood and adolescent obesity: a review

G Colmenarejo - Nutrients, 2020 - mdpi.com
The prevalence of childhood and adolescence overweight an obesity is raising at an
alarming rate in many countries. This poses a serious threat to the current and near-future …

A survey on nature-inspired medical image analysis: a step further in biomedical data integration

L Rundo, C Militello, S Vitabile, G Russo… - Fundamenta …, 2020 - content.iospress.com
Natural phenomena and mechanisms have always intrigued humans, inspiring the design of
effective solutions for real-world problems. Indeed, fascinating processes occur in nature …

Applications of network analysis to routinely collected health care data: a systematic review

JC Brunson, RC Laubenbacher - Journal of the American …, 2018 - academic.oup.com
Objective To survey network analyses of datasets collected in the course of routine
operations in health care settings and identify driving questions, methods, needs, and …

Big data as a value generator in decision support systems: A literature review

G Grander, LF da Silva… - Revista de Gestão, 2021 - emerald.com
Purpose This paper aims to analyze how decision support systems manage Big data to
obtain value. Design/methodology/approach A systematic literature review was performed …

A network analysis to identify lung cancer comorbid diseases

HC Rustamaji, YS Suharini, AA Permana… - Applied Network …, 2022 - Springer
Cancer patients with comorbidities face various life problems, health costs, and quality of
life. Therefore, determining comorbid diseases would significantly affect the treatment of …

Higher-order networks of diabetes comorbidities: disease trajectories that matter

SJ Krieg, DH Robertson, MP Pradhan… - 2020 IEEE …, 2020 - ieeexplore.ieee.org
Networks are powerful and flexible structures for modeling relationships in medical and
biological systems, but in a traditional first-order network representation, an edge typically …

Multimorbidity in neurodegenerative diseases: a network analysis

M Amini, A Bagheri, M P. Paulus… - Informatics for Health and …, 2024 - Taylor & Francis
The socioeconomic costs of neurodegenerative diseases (NDs) are highly affected by
comorbidities. This study aims to enhance our understanding of the prevalent complications …

Sensitivity of comorbidity network analysis

JC Brunson, TP Agresta, RC Laubenbacher - JAMIA open, 2020 - academic.oup.com
Objectives Comorbidity network analysis (CNA) is a graph-theoretic approach to systems
medicine based on associations revealed from disease co-occurrence data. Researchers …

A network-based approach to explore comorbidity patterns among community-dwelling older adults living alone

C Lee, YH Park, B Cho, HA Lee - GeroScience, 2024 - Springer
The detailed comorbidity patterns of community-dwelling older adults have not yet been
explored. This study employed a network-based approach to investigate the comorbidity …