Current pharmacological treatments for depression fail to produce adequate remission in a
significant proportion of patients. Increasingly, other systems, such as the microbiome–gut …

The reelin signaling pathway has been established as an important regulator of cell
migration during development of the central nervous system, and disruptions in reelin …

Reelin, an extracellular matrix protein with putative antidepressant-like properties, becomes
dysregulated by chronic stress. Improvement in cognitive dysfunction and depression-like …

Diverse pathogens are detected in Alzheimer's disease (AD) brains. A bioinformatics survey
showed that AD genome-wide association study (GWAS) genes (localized in bone marrow …

RAS signalling through phosphoinositide 3-kinase (PI3-Kinase) has been shown to have an
essential role in tumour initiation and maintenance. RAS also regulates cell motility and …

Reelin is an extracellular matrix protein that plays a critical role in neuronal migration. Here
we show that the mucosa of human colon expresses reelin, its receptors ApoER2 and …

Alzheimer's disease (AD) accounts for most dementia cases, but we lack a complete
understanding of the mechanisms responsible for the core pathology associated with the …

Reelin is an extracellular matrix protein first known for its key role in neuronal migration.
Studies in rodent small intestine suggested that reelin protects the organism from intestinal …

Intestinal myofibroblasts secrete substances that control organogenesis and wound repair of
the intestine. The myofibroblasts of the rat small intestine express reelin and the present …

Autosomal recessive ataxia telangiectasia (AT) is characterized by radiosensitivity,
immunodeficiency, and cerebellar neurodegeneration. AT is caused by inactivating …