Discovery of a nanomolar inhibitor of lung adenocarcinoma in vitro

JR Shelton, J Balzarini, MA Peterson - Bioorganic & Medicinal Chemistry …, 2014 - Elsevier
Efficient methods for the preparation of 5′-substituted 5′-amino-5′-deoxy-N 6-
ureidoadenosine derivatives are described. Compounds were screened for antiproliferative …

Synthesis of biurets via TMSNCO addition to 1-aminosugars: application in the de novo synthesis of dC oxidation products

V Tsoulougian, EE Psykarakis, T Gimisis - Organic & Biomolecular …, 2019 - pubs.rsc.org
The reaction between 1-aminosugars and trimethylisocyanate (TMSNCO) was optimised as
a one-step synthetic strategy for the synthesis of sugar biurets. This protocol was …

[图书][B] Synthesis and Biological Evaluation of Small Molecule Inhibitors of BMPR1b

PAM Tello - 2016 - search.proquest.com
Methods for preparing an array of potential small molecule inhibitors of Bone Morphogenetic
Protein Receptor 1b (BMPR1b) are described. Target molecules were prepared from two …