Phosphorylation-Dependent Regulation of Guanylyl Cyclase (GC)-A and Other Membrane GC Receptors

LR Potter - Endocrine Reviews, 2024 - academic.oup.com
Receptor guanylyl cyclases (GCs) are single membrane spanning, multidomain enzymes,
that synthesize cGMP in response to natriuretic peptides or other ligands. They are …

The 10th International Conference on cGMP 2022: recent trends in cGMP research and development—meeting report

A Friebe, JR Kraehling, M Russwurm… - Naunyn-schmiedeberg's …, 2023 - Springer
Increasing cGMP is a unique therapeutic principle, and drugs inhibiting cGMP-degrading
enzymes or stimulating cGMP production are approved for the treatment of various diseases …

Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase

JR Egbert, I Silbern, TF Uliasz, KM Lowther… - Biology of …, 2024 - academic.oup.com
In response to luteinizing hormone (LH), multiple proteins in rat and mouse granulosa cells
are rapidly dephosphorylated, but the responsible phosphatases remain to be identified …