During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Complex and dynamic networks of molecules are involved in human diseases. High-
throughput technologies enable omics studies interrogating thousands to millions of makers …

Psychiatric disorders represent a great medical and social challenge and people suffering
from these conditions face many impairments regarding personal and professional life. In …

Recent improvements in high-throughput proteomic approaches are likely to constitute an
essential advance in biomarker discovery, holding promise for improved personalized care …

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by
behavioral alterations and currently affect about 1% of children. Significant genetic factors …

The development of human-induced pluripotent stem cells (hiPSCs) has made possible
patient-specific modeling across the spectrum of human disease. Here, we discuss recent …

Research investigating the pathophysiology of schizophrenia has not yet precisely defined
the molecular phenotype of this disorder. Many studies have investigated cellular …

Schizophrenia is an incurable and debilitating mental disorder that may affect up to 1% of
the world population. Morphological, electrophysiological, and neurophysiological studies …

Background Some evidence support the notion that microglia activation in acute state of
schizophrenia might contribute to damage of oligodendrocytes and myelinated fibers …