Cardiac organoids differentiated from induced pluripotent stem cells are emerging as a
promising platform for pre-clinical drug screening, assessing cardiotoxicity, and disease …

Drug-induced cardiotoxicity is a potentially severe side effect that can alter the contractility
and electrophysiology of the cardiomyocytes. Cardiotoxicity is generally assessed through …

The limitations of conventional animal tests and two-dimensional cell culture hinder their
advancement in fundamental research and clinical/translational applications. As an …

Heart disease remains a leading cause of global mortality, underscoring the need for
advanced technologies to study cardiovascular diseases and develop effective treatments …

Preclinical drug screening for cardiac toxicity has traditionally relied on observing changes
in cardiomyocytes' electrical activity, primarily through invasive patch clamp techniques or …

The exploration of in vitro cell cultures holds pivotal significance in biological studies,
providing a crucial lens through which we examine cellular responses to external stimuli …

This work demonstrates a dual simultaneous measurement platform that can be used for
drug induced cardiac toxicity screening. The platform consists of a cantilever with strain …