Although blood suppliers are seeing short-term reductions in blood demand as a result of
initiatives in patient blood management, modelling suggests that during the next 5–10 years …

Background New concepts in resuscitation from hemorrhagic shock (or renewed interest in
older concepts) have been emerging in recent years. A report from 1993 noted that initial …

Objective: The aim of this study was to identify a mortality benefit with the use of whole blood
(WB) as part of the resuscitation of bleeding trauma patients. Background: Blood component …

Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It
contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in …

PURPOSE Following US military implementation of a cold-stored whole blood program,
several US trauma centers have begun incorporating uncrossmatched, group O cold-stored …

Objectives: To determine whether resuscitation of severely injured patients with modified
whole blood (mWB) resulted in fewer overall transfusions compared with component …

Acute Traumatic Coagulopathy occurs immediately after massive trauma when shock,
hypoperfusion, and vascular damage are present. Mechanisms for this acute coagulopathy …

Importance Whole-blood (WB) resuscitation has gained renewed interest among civilian
trauma centers. However, there remains insufficient evidence that WB as an adjunct to …

Background Acute blood loss in trauma requires quick identification and action to restore
circulating volume and save the patient. Massive transfusion protocols (MTPs) have become …

Hemorrhage is a top cause of death after injury and is the leading cause of potentially
preventable trauma deaths. 1–3 In contrast to other causes of trauma death, such as …