Solid-state nanopore sensors
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …
based, single-molecule analysis of the key building blocks of life, including nucleic acids …
The new era of high-throughput nanoelectrochemistry
To acquire a deeper understanding of electrochemical systems requires techniques that
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …
In situ solid-state nanopore fabrication
Nanopores in solid-state membranes are promising for a wide range of applications
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …
including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data …
Nanoscale tweezers for single-cell biopsies
Much of the functionality of multicellular systems arises from the spatial organization and
dynamic behaviours within and between cells. Current single-cell genomic methods only …
dynamic behaviours within and between cells. Current single-cell genomic methods only …
Overview of the materials design and sensing strategies of nanopore devices
L Liang, F Qin, S Wang, J Wu, R Li, Z Wang… - Coordination Chemistry …, 2023 - Elsevier
Nanopore platform holds a great fascination that attracts increasing interests in research and
leads the development of various domains. Herein we first briefly introduce the …
leads the development of various domains. Herein we first briefly introduce the …
Label-free optical analysis of biomolecules in solid-state nanopores: toward single-molecule protein sequencing
Sequence identification of peptides and proteins is central to proteomics. Protein
sequencing is mainly conducted by insensitive mass spectroscopy because proteins cannot …
sequencing is mainly conducted by insensitive mass spectroscopy because proteins cannot …
Real-Time Monitoring of Exosomes Secretion from Single Cell Using Dual-Nanopore Biosensors
H Zhang, X Zheng, T Zhao, Y Chen, Y Luo, Y Dong… - ACS …, 2023 - ACS Publications
Exosomes secreted from cells carry rich information from their parent cells, representing a
promising biomarker for investigation of diseases. We develop a dual-nanopore biosensor …
promising biomarker for investigation of diseases. We develop a dual-nanopore biosensor …
Development of dual-nanopore biosensors for detection of intracellular dopamine and dopamine efflux from single PC12 cell
T Zhao, JW Wang, HS Zhang, X Zheng… - Analytical …, 2022 - ACS Publications
Detection of neurotransmitters at the single-cell level is essential for understanding the
related biological processes and neurodegenerative diseases. We report a dual-nanopore …
related biological processes and neurodegenerative diseases. We report a dual-nanopore …
Solid‐State Quad‐Nanopore Array for High‐Resolution Single‐Molecule Analysis and Discrimination
R Hu, R Zhu, G Wei, Z Wang, ZY Gu… - Advanced …, 2023 - Wiley Online Library
The ability to detect and distinguish biomolecules at the single‐molecule level is at the
forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time …
forefront of today's biomedicine and analytical chemistry research. Increasing the dwell time …
Interfacing Aptamer-Modified Nanopipettes with Neuronal Media and Ex Vivo Brain Tissue
A Stuber, A Cavaccini, A Manole… - ACS Measurement …, 2023 - ACS Publications
Aptamer-functionalized biosensors exhibit high selectivity for monitoring neurotransmitters in
complex environments. We translated nanoscale aptamer-modified nanopipette sensors to …
complex environments. We translated nanoscale aptamer-modified nanopipette sensors to …