NEURONAL SUBSTRATES OF COMPLEX BEHAVIORS IN C. ELEGANS
M Bono, A Villu Maricq - Annu. Rev. Neurosci., 2005 - annualreviews.org
A current challenge in neuroscience is to bridge the gaps between genes, proteins, neurons,
neural circuits, and behavior in a single animal model. The nematode Caenorhabditis …
neural circuits, and behavior in a single animal model. The nematode Caenorhabditis …
Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum …
F Calahorro, M Ruiz-Rubio - Invertebrate neuroscience, 2011 - Springer
The nematode Caenorhabditis elegans has a very well-defined and genetically tractable
nervous system which offers an effective model to explore basic mechanistic pathways that …
nervous system which offers an effective model to explore basic mechanistic pathways that …
What keeps C. elegans regular: the genetics of defecation
R Branicky, S Hekimi - TRENDS in Genetics, 2006 - cell.com
Caenorhabditis elegans exhibits a repertoire of behaviors that can be studied by genetic,
anatomical and pharmacological approaches. Defecation is one of the simpler behaviors …
anatomical and pharmacological approaches. Defecation is one of the simpler behaviors …
[HTML][HTML] Endoderm development in Caenorhabditis elegans: the synergistic action of ELT-2 and-7 mediates the specification→ differentiation transition
EM Sommermann, KR Strohmaier, MF Maduro… - Developmental …, 2010 - Elsevier
The transition from specification of cell identity to the differentiation of cells into an
appropriate and enduring state is critical to the development of embryos. Transcriptional …
appropriate and enduring state is critical to the development of embryos. Transcriptional …
Intestinal Ca2+ wave dynamics in freely moving C. elegans coordinate execution of a rhythmic motor program
Defecation in the nematode worm Caenorhabditis elegans is a highly rhythmic behavior that
is regulated by a Ca2+ wave generated in the 20 epithelial cells of the intestine, in part …
is regulated by a Ca2+ wave generated in the 20 epithelial cells of the intestine, in part …
Using C. elegans to Decipher the Cellular and Molecular Mechanisms Underlying Neurodevelopmental Disorders
Neurodevelopmental disorders such as epilepsy, intellectual disability (ID), and autism
spectrum disorders (ASDs) occur in over 2% of the population, as the result of genetic …
spectrum disorders (ASDs) occur in over 2% of the population, as the result of genetic …
A presynaptic function of shank protein in Drosophila
Human genetic studies support that loss-of-function mutations in the SH3 domain and
ankyrin repeat containing family proteins (SHANK1-3), the large synaptic scaffolding …
ankyrin repeat containing family proteins (SHANK1-3), the large synaptic scaffolding …
Worms on the spectrum-C. elegans models in autism research
K Schmeisser, JA Parker - Experimental neurology, 2018 - Elsevier
The small non-parasitic nematode Caenorhabditis elegans is widely used in neuroscience
thanks to its well-understood development and lineage of the nervous system. Furthermore …
thanks to its well-understood development and lineage of the nervous system. Furthermore …
JNK Signaling Positively Regulates Acute Ethanol Tolerance in C. elegans
C Jee, E Batsaikhan - International Journal of Molecular Sciences, 2024 - mdpi.com
Alcohol use disorder (AUD) is a chronic neurobehavioral condition characterized by a cycle
of tolerance development, increased consumption, and reinstated craving and seeking …
of tolerance development, increased consumption, and reinstated craving and seeking …
The InsP3 receptor: its role in neuronal physiology and neurodegeneration
S Banerjee, G Hasan - Bioessays, 2005 - Wiley Online Library
The InsP3 receptor is a ligand‐gated channel that releases Ca2+ from intracellular stores in
a variety of cell types, including neurons. Genetic studies from vertebrate and invertebrate …
a variety of cell types, including neurons. Genetic studies from vertebrate and invertebrate …