Postoperative cognitive dysfunction and noncardiac surgery

LA Evered, BS Silbert - Anesthesia & Analgesia, 2018 - journals.lww.com
Postoperative cognitive dysfunction (POCD) is an objectively measured decline in cognition
postoperatively compared with preoperative function. POCD has been considered in the …

The role of neuroinflammation in postoperative cognitive dysfunction: moving from hypothesis to treatment

SA Safavynia, PA Goldstein - Frontiers in psychiatry, 2019 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …

Anesthesiology and cognitive impairment: a narrative review of current clinical literature

JC Belrose, RR Noppens - BMC anesthesiology, 2019 - Springer
Background The impact of general anesthesia on cognitive impairment is controversial and
complex. A large body of evidence supports the association between exposure to surgery …

[HTML][HTML] State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018

E Mahanna-Gabrielli, KJ Schenning, LI Eriksson… - British journal of …, 2019 - Elsevier
Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …

Postoperative cognitive dysfunction: minding the gaps in our knowledge of a common postoperative complication in the elderly

M Berger, J Nadler, J Browndyke… - Anesthesiology …, 2015 - pmc.ncbi.nlm.nih.gov
Ever since Bedford's seminal Lancet case series in 1955, we have known that perioperative
care is sometimes followed by significant cognitive dysfunction (1). Although the safety of …

Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats

MB Netto, AN de Oliveira Junior, M Goldim… - Brain, behavior, and …, 2018 - Elsevier
Postoperative cognitive dysfunction (POCD) is defined by cognitive impairment determined
by neuropsychological tests from before to after surgery. Several mechanisms have been …

Best practices for postoperative brain health: recommendations from the fifth international perioperative neurotoxicity working group

M Berger, KJ Schenning, CH Brown IV… - Anesthesia & …, 2018 - journals.lww.com
As part of the American Society of Anesthesiology Brain Health Initiative goal of improving
perioperative brain health for older patients, over 30 experts met at the fifth International …

[HTML][HTML] Postoperative cognitive dysfunction: current developments in mechanism and prevention

W Wang, Y Wang, H Wu, L Lei, S Xu… - … medical journal of …, 2014 - ncbi.nlm.nih.gov
Postoperative cognitive dysfunction (POCD) is a subtle disorder of thought processes, which
may influence isolated domains of cognition and has a significant impact on patient health …

Post‐operative cognitive dysfunction at 3 months in adults after non‐cardiac surgery: a qualitative systematic review

S Paredes, L Cortínez, V Contreras… - Acta Anaesthesiologica …, 2016 - Wiley Online Library
Background Post‐operative cognitive dysfunction is defined as a decline in cognitive
functions that occurs after surgery, but different diagnostic criteria and incidences have been …

Preoperative cognitive stratification of older elective surgical patients: a cross-sectional study

DJ Culley, D Flaherty, S Reddy, MC Fahey… - Anesthesia & …, 2016 - journals.lww.com
BACKGROUND: Preexisting cognitive impairment is emerging as a predictor of poor
postoperative outcomes in seniors. We hypothesized that preoperative cognitive screening …