Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Genomics of microbial plasmids: classification and identification based on replication and transfer systems and host taxonomy

M Shintani, ZK Sanchez, K Kimbara - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …

CheckV assesses the quality and completeness of metagenome-assembled viral genomes

S Nayfach, AP Camargo, F Schulz… - Nature …, 2021 - nature.com
Millions of new viral sequences have been identified from metagenomes, but the quality and
completeness of these sequences vary considerably. Here we present CheckV, an …

PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures

PS Krawczyk, L Lipinski… - Nucleic acids research, 2018 - academic.oup.com
Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …

CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

DH Parks, M Imelfort, CT Skennerton… - Genome …, 2015 - genome.cshlp.org
Large-scale recovery of genomes from isolates, single cells, and metagenomic data has
been made possible by advances in computational methods and substantial reductions in …

Metagenomic data assembly–the way of decoding unknown microorganisms

AL Lapidus, AI Korobeynikov - Frontiers in Microbiology, 2021 - frontiersin.org
Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …

Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance

T Wein, NF Hülter, I Mizrahi, T Dagan - Nature communications, 2019 - nature.com
Plasmid acquisition is an important mechanism of rapid adaptation and niche expansion in
prokaryotes. Positive selection for plasmid-coded functions is a major driver of plasmid …

Genomic characterization of nontuberculous mycobacteria

T Fedrizzi, CJ Meehan, A Grottola, E Giacobazzi… - Scientific reports, 2017 - nature.com
Mycobacterium tuberculosis and Mycobacterium leprae have remained, for many years, the
primary species of the genus Mycobacterium of clinical and microbiological interest. The …

<? mode longmeta?> IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata

AP Camargo, L Call, S Roux, S Nayfach… - Nucleic acids …, 2024 - academic.oup.com
Plasmids are mobile genetic elements found in many clades of Archaea and Bacteria. They
drive horizontal gene transfer, impacting ecological and evolutionary processes within …

Plasmid-mediated transfer of antibiotic resistance genes in soil

M Meng, Y Li, H Yao - Antibiotics, 2022 - mdpi.com
Due to selective pressure from the widespread use of antibiotics, antibiotic resistance genes
(ARGs) are found in human hosts, plants, and animals and virtually all natural environments …