The case for the development of a Chagas disease vaccine: why? How? When?
E Dumonteil, C Herrera - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Chagas disease is a major neglected tropical disease, transmitted predominantly by
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …
triatomine insect vectors, but also through congenital and oral routes. While endemic in the …
Prevalence and transmission of the most relevant zoonotic and vector-borne pathogens in the Yucatan peninsula: A review
MF Sánchez-Soto, O Gaona… - PLOS Neglected …, 2024 - journals.plos.org
Background Habitat modification and land use changes impact ecological interactions and
alter the relationships between humans and nature. Mexico has experienced significant …
alter the relationships between humans and nature. Mexico has experienced significant …
The economic value of identifying and treating Chagas disease patients earlier and the impact on Trypanosoma cruzi transmission
SM Bartsch, CM Avelis, L Asti… - PLoS neglected …, 2018 - journals.plos.org
Background The World Health Organization's 2020 Goals for Chagas disease include
access to antiparasitic treatment and care of all infected/ill patients. Policy makers need to …
access to antiparasitic treatment and care of all infected/ill patients. Policy makers need to …
Effectiveness of fluralaner treatment regimens for the control of canine Chagas disease: A mathematical modeling study
Background Canine Chagas disease is caused by the protozoan parasite Trypanosoma
cruzi and transmitted by insect triatomine vectors known as kissing bugs. The agent can …
cruzi and transmitted by insect triatomine vectors known as kissing bugs. The agent can …
Modeling the impact of xenointoxication in dogs to halt Trypanosoma cruzi transmission
Background Chagas disease, a vector-borne parasitic disease caused by Trypanosoma
cruzi, affects millions in the Americas. Dogs are important reservoirs of the parasite. Under …
cruzi, affects millions in the Americas. Dogs are important reservoirs of the parasite. Under …
[HTML][HTML] Trypanosoma cruzi infection in dogs along the US-Mexico border: R0 changes with vector species composition
Infection with Trypanosoma cruzi, etiological agent of Chagas disease, is common in US
government working dogs along the US-Mexico border. This 3145 km long border …
government working dogs along the US-Mexico border. This 3145 km long border …
[PDF][PDF] Modelling Trypanosoma cruzi-Trypanosoma rangeli co-infection and pathogenic effect on Chagas disease spread
A mathematical model is developed to investigate the impact of Trypanosoma cruzi and
Trypanosoma rangeli co-infection and Trypanosoma rangeli-induced pathogenicity of …
Trypanosoma rangeli co-infection and Trypanosoma rangeli-induced pathogenicity of …
Vaccine design against chagas disease focused on the use of nucleic acids
E Maldonado, S Morales-Pison, F Urbina, A Solari - Vaccines, 2022 - mdpi.com
Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central
and South America. However, it has spread around the world and affects several million …
and South America. However, it has spread around the world and affects several million …
Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising …
Drug therapy for Chagas disease remains a major challenge as potential candidate drugs
have failed clinical trials. Currently available drugs have limited efficacy and induce serious …
have failed clinical trials. Currently available drugs have limited efficacy and induce serious …
A Scoping Review of Mathematical Models Used to Investigate the Role of Dogs in Chagas Disease Transmission
Simple Summary Chagas disease-caused by the parasite Trypanosoma cruzi and vectored
by triatomine insects ('kissing bugs')-poses a serious threat to human and dog health …
by triatomine insects ('kissing bugs')-poses a serious threat to human and dog health …