The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …

Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level
of gene function and regulation. Thus, characterizing the structures and interactions of …

RNA is a unique bio-macromolecule that can both record genetic information and perform
biological functions in a variety of molecular processes, including transcription, splicing …

SUMMARY RNA G-quadruplex (rG4) secondary structures are proposed to play key roles in
fundamental biological processes that include the modulation of transcriptional, co …

RNA molecules are important players in all domains of life and the study of the relationship
between their multiple flexible states and the associated biological roles has increased in …

A large portion of eukaryotic genes are associated with noncoding, natural antisense
transcripts (NATs). Despite sharing extensive sequence complementarity with their sense …

While the protein composition of various yeast 60S ribosomal subunit assembly
intermediates has been studied in detail, little is known about ribosomal RNA (rRNA) …

Background Structure profiling experiments provide single‐nucleotide information on RNA
structure. Recent advances in chemistry combined with application of high‐throughput …

RNA folds into intricate structures that are crucial for its functions and regulations. To date, a
multitude of approaches for probing structures of the whole transcriptome, ie., RNA …

Establishing a link between RNA structure and function remains a great challenge in RNA
biology. The emergence of high-throughput structure profiling experiments is revolutionizing …