Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment

MS Khan, BHJ Gowda, WH Almalki, T Singh… - Drug Discovery …, 2023 - Elsevier
Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

[HTML][HTML] Nanomedicine potentiates mild photothermal therapy for tumor ablation

Z Jiang, T Li, H Cheng, F Zhang, X Yang… - Asian Journal of …, 2021 - Elsevier
The booming photothermal therapy (PTT) has achieved great progress in non-invasive
oncotherapy, and paves a novel way for clinical oncotherapy. Of note, mild temperature PTT …

A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies

B Youden, R Jiang, AJ Carrier, MR Servos, X Zhang - ACS nano, 2022 - ACS Publications
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …

[HTML][HTML] Promising strategy of mPTP modulation in cancer therapy: an emerging progress and future insight

M Waseem, BD Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Cancer has been progressively a major global health concern. With this developing global
concern, cancer determent is one of the most significant public health challenges of this era …

[HTML][HTML] Mitochondrial targeting theranostic nanomedicine and molecular biomarkers for efficient cancer diagnosis and therapy

SK Rout, V Priya, A Setia, AK Mehata, S Mohan… - Biomedicine & …, 2022 - Elsevier
Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

Small molecules targeting mitochondria as an innovative approach to cancer therapy

OS Kamble, R Chatterjee, KG Abishek, J Chandra… - Cellular …, 2024 - Elsevier
Cellular death evasion is a defining characteristic of human malignancies and a significant
contributor to therapeutic inefficacy. As a result of oncogenic inhibition of cell death …

LC-HRMS analysis of corn mint Mentha arvensis L. for anticancer activity against triple-negative breast cancer targeting inflammatory and apoptosis signaling …

BB Pratyusha, RMS Samuvel, S Nivetha… - New Journal of …, 2024 - pubs.rsc.org
In this study, the methanol extract of Mentha arvensis (MMA) was assessed for anticancer
activity against triple-negative breast cancer MDA-MB-231 cells and the metabolomic …

[HTML][HTML] A nanocomposite competent to overcome cascade drug resistance in ovarian cancer via mitochondria dysfunction and NO gas synergistic therapy

M Zhong, P Liang, Z Feng, X Yang, G Li, R Sun… - Asian Journal of …, 2023 - Elsevier
Ovarian cancer (OC) is one of the most common and recurring malignancies in gynecology.
Patients with relapsed OC always develop" cascade drug resistance"(CDR) under repeated …

[HTML][HTML] Advances in intracellular calcium signaling reveal untapped targets for cancer therapy

A Sharma, GT Ramena, RC Elble - Biomedicines, 2021 - mdpi.com
Intracellular Ca2+ distribution is a tightly regulated process. Numerous Ca2+ chelating,
storage, and transport mechanisms are required to maintain normal cellular physiology …

Mitochondrial signaling pathways and their role in cancer drug resistance

A Sharma, T Virmani, G Kumar, A Sharma, R Virmani… - Cellular …, 2024 - Elsevier
Mitochondria, traditionally known as cellular powerhouses, now emerge as critical signaling
centers influencing cancer progression and drug resistance. The review highlights the role …