Unravelling the potential of mitochondria-targeted liposomes for enhanced cancer treatment
Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …
[HTML][HTML] Nanomedicine potentiates mild photothermal therapy for tumor ablation
Z Jiang, T Li, H Cheng, F Zhang, X Yang… - Asian Journal of …, 2021 - Elsevier
The booming photothermal therapy (PTT) has achieved great progress in non-invasive
oncotherapy, and paves a novel way for clinical oncotherapy. Of note, mild temperature PTT …
oncotherapy, and paves a novel way for clinical oncotherapy. Of note, mild temperature PTT …
A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …
[HTML][HTML] Promising strategy of mPTP modulation in cancer therapy: an emerging progress and future insight
Cancer has been progressively a major global health concern. With this developing global
concern, cancer determent is one of the most significant public health challenges of this era …
concern, cancer determent is one of the most significant public health challenges of this era …
[HTML][HTML] Mitochondrial targeting theranostic nanomedicine and molecular biomarkers for efficient cancer diagnosis and therapy
Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …
microenvironments and their dysfunction is associated with an extensive array of illnesses …
Small molecules targeting mitochondria as an innovative approach to cancer therapy
OS Kamble, R Chatterjee, KG Abishek, J Chandra… - Cellular …, 2024 - Elsevier
Cellular death evasion is a defining characteristic of human malignancies and a significant
contributor to therapeutic inefficacy. As a result of oncogenic inhibition of cell death …
contributor to therapeutic inefficacy. As a result of oncogenic inhibition of cell death …
LC-HRMS analysis of corn mint Mentha arvensis L. for anticancer activity against triple-negative breast cancer targeting inflammatory and apoptosis signaling …
BB Pratyusha, RMS Samuvel, S Nivetha… - New Journal of …, 2024 - pubs.rsc.org
In this study, the methanol extract of Mentha arvensis (MMA) was assessed for anticancer
activity against triple-negative breast cancer MDA-MB-231 cells and the metabolomic …
activity against triple-negative breast cancer MDA-MB-231 cells and the metabolomic …
[HTML][HTML] A nanocomposite competent to overcome cascade drug resistance in ovarian cancer via mitochondria dysfunction and NO gas synergistic therapy
M Zhong, P Liang, Z Feng, X Yang, G Li, R Sun… - Asian Journal of …, 2023 - Elsevier
Ovarian cancer (OC) is one of the most common and recurring malignancies in gynecology.
Patients with relapsed OC always develop" cascade drug resistance"(CDR) under repeated …
Patients with relapsed OC always develop" cascade drug resistance"(CDR) under repeated …
[HTML][HTML] Advances in intracellular calcium signaling reveal untapped targets for cancer therapy
Intracellular Ca2+ distribution is a tightly regulated process. Numerous Ca2+ chelating,
storage, and transport mechanisms are required to maintain normal cellular physiology …
storage, and transport mechanisms are required to maintain normal cellular physiology …
Mitochondrial signaling pathways and their role in cancer drug resistance
Mitochondria, traditionally known as cellular powerhouses, now emerge as critical signaling
centers influencing cancer progression and drug resistance. The review highlights the role …
centers influencing cancer progression and drug resistance. The review highlights the role …