A concise review on recent development of indole derivatives for anticancer activities
Indole heterocycles have been considered as noteworthy associated hybrids because of
their diverse applications in organic synthesis, and coordination chemistry, as well as in the …
their diverse applications in organic synthesis, and coordination chemistry, as well as in the …
Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective
The importance of indole‐based heterocycle scaffolds in medicinal chemistry has increased
as a result of their significant pharmacological and biological characteristics. These …
as a result of their significant pharmacological and biological characteristics. These …
Spectroscopic, theoretical and computational investigations of novel benzo [b] thiophene based ligand and its M (II) complexes: As high portentous antimicrobial and …
NG Yernale, BS Mathada, S Shivprasad… - … Acta Part A: Molecular …, 2023 - Elsevier
The reaction of 3-chlorobenzo [b] thiophene-2-carbohydrazide with 4-(diethylamino)
salicylaldehyde gave the new ligand; 3-chloro-N'-(4-(diethylamino)-2-hydroxybenzylidene) …
salicylaldehyde gave the new ligand; 3-chloro-N'-(4-(diethylamino)-2-hydroxybenzylidene) …
Exploration of Indolo [3, 2c] isoquinoline derived triazoles as potential antimicrobial and DNA cleavage agents: synthesis, DFT calculations, and molecular modeling …
Indole and its derivatives are well-known assorted motif in drug design and development.
We here in reporting synthesis of new 9-chloro-1-(4-substituted phenyl)-12H-indolo [2, 3 …
We here in reporting synthesis of new 9-chloro-1-(4-substituted phenyl)-12H-indolo [2, 3 …
Novel pyrimidines as COX-2 selective inhibitors: synthesis, DFT analysis, molecular docking and dynamic simulation studies
BS Mathada, NJ Basha, M Javeed… - Journal of …, 2024 - Taylor & Francis
Pyrimidine and its derivatives are associated with varieties of biological properties.
Therefore, we herein reported the synthesis of four novel pyrimidines (2, 3, and 4a, b) …
Therefore, we herein reported the synthesis of four novel pyrimidines (2, 3, and 4a, b) …
Synthesis, structural investigations, DFT calculations, and molecular docking studies of novel 2-(substituted-aryloxymethyl)-5-(pyridin-4-yl)-1, 3, 4-oxadiazoles: Highly …
M Datar, R Dhanwad, M Javeed… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Abstract We report derivatives of 2, 5-disubstituted-1, 3, 4-oxadiazole as powerful anti-TB
and antioxidant compounds. Using substituted aryloxy acetic acids (2a–f) and isoniazid (3) …
and antioxidant compounds. Using substituted aryloxy acetic acids (2a–f) and isoniazid (3) …
Design, synthesis, biological evaluation on immune cell proliferation, crystal structures, spectroscopic characterizations, DFT calculations, ADME analysis, and …
R Sghyar, SM Basavarajaiah, A Chda… - Journal of Molecular …, 2023 - Elsevier
Abstract The new 5-(substituted)-3-(1, 2, 3, 4-di-O-isopropylidene-(D)-galactopyranose)
tetrazoles (1c-8c) have been achieved by using as starting materials substituted tetrazole …
tetrazoles (1c-8c) have been achieved by using as starting materials substituted tetrazole …
Synthesis, characterization, DFT analysis, biological evaluation, and molecular docking of Schiff Base derived from Isatin–isoniazid and its metal (II) complexes
R Nalini, SM Basavarajaiah, GY Nagesh… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A series of octahedral Zn (II), Cu (II), Ni (II), and Co (II) complexes have been synthesized
with ONO donor Schiff base ligand N'-(6-chloro-2-oxoindolin-3-ylidene) nicotinohydrazide …
with ONO donor Schiff base ligand N'-(6-chloro-2-oxoindolin-3-ylidene) nicotinohydrazide …
Synthesis, Antioxidant and Antiproliferative Evaluation, Molecular Docking and DFT Studies of Some Novel Coumarin and Fused Coumarin Derivatives
MAS Gouda, MAI Salem, MI Marzouk… - Chemistry & …, 2023 - Wiley Online Library
Abstract N′‐[(4‐Chloro‐2‐oxo‐2H‐chromen‐3‐yl) methylene]‐2‐cyanoacetohydrazide (3)
was synthesized in excellent yield from the condensation of 4‐Chloro‐2‐oxo‐2H‐chromene …
was synthesized in excellent yield from the condensation of 4‐Chloro‐2‐oxo‐2H‐chromene …
In silico, in vitro and docking exploration for some novel coordination complexes derived from bioactive indole moiety
Abstract The reaction of 5-methyl-3-phenyl-1H-indole-2-carbohydrazide with 4-
methoxybenzaldehyde gave the new ligand molecule; N'-(4-methoxybenzylidene)-5-methyl …
methoxybenzaldehyde gave the new ligand molecule; N'-(4-methoxybenzylidene)-5-methyl …