Large-area interfaces for single-molecule label-free bioelectronic detection
Bioelectronic transducing surfaces that are nanometric in size have been the main route to
detect single molecules. Though enabling the study of rarer events, such methodologies are …
detect single molecules. Though enabling the study of rarer events, such methodologies are …
[HTML][HTML] Uncovering the depths of the human proteome: antibody-based technologies for ultrasensitive multiplexed protein detection and quantification
AH Ren, EP Diamandis, V Kulasingam - Molecular & Cellular Proteomics, 2021 - ASBMB
Probing the human proteome in tissues and biofluids such as plasma is attractive for
biomarker and drug target discovery. Recent breakthroughs in multiplex, antibody-based …
biomarker and drug target discovery. Recent breakthroughs in multiplex, antibody-based …
High-throughput, high-multiplex digital protein detection with attomolar sensitivity
A major challenge in many clinical diagnostic applications is the measurement of low-
abundance proteins and other biomolecules in biological fluids. Digital technologies such as …
abundance proteins and other biomolecules in biological fluids. Digital technologies such as …
Ultrasensitive measurement of both SARS-CoV-2 RNA and antibodies from saliva
D Ter-Ovanesyan, T Gilboa, R Lazarovits… - Analytical …, 2021 - ACS Publications
Tests for COVID-19 generally measure SARS-CoV-2 viral RNA from nasal swabs or
antibodies against the virus from blood. It has been shown, however, that both viral particles …
antibodies against the virus from blood. It has been shown, however, that both viral particles …
[HTML][HTML] Emerging advances of detection strategies for tumor-derived exosomes
H Cheng, Q Yang, R Wang, R Luo, S Zhu, M Li… - International Journal of …, 2022 - mdpi.com
Exosomes derived from tumor cells contain various molecular components, such as
proteins, RNA, DNA, lipids, and carbohydrates. These components play a crucial role in all …
proteins, RNA, DNA, lipids, and carbohydrates. These components play a crucial role in all …
A single snapshot multiplex immunoassay platform utilizing dense test lines based on engineered beads
Co-circulation of coronavirus disease 2019 (COVID-19) and dengue fever has been
reported. Accurate and timely multiplex diagnosis is required to prevent future pandemics …
reported. Accurate and timely multiplex diagnosis is required to prevent future pandemics …
Recent progress on digital immunoassay: how to achieve ultrasensitive, multiplex and clinical accessible detection?
Y Zhang, H Gu, H Xu - Sensors & Diagnostics, 2024 - pubs.rsc.org
The detection of low abundance proteins in physiological samples is of good importance on
clinical diagnostics and pathology research. However, the protein biomarkers that can be …
clinical diagnostics and pathology research. However, the protein biomarkers that can be …
[HTML][HTML] Rapid multiplex assay of SARS-CoV-2 antigens based on magnetic Janus photonic barcodes
SARS-CoV-2 has been causing severe impacts on all aspects of society for more than three
years. Antigen immunoassay is the main detection method of SARS-CoV-2 at present. Here …
years. Antigen immunoassay is the main detection method of SARS-CoV-2 at present. Here …
Monitoring Melanoma Responses to STING Agonism and Focused Ultrasound Thermal Ablation Using Microneedles and Ultrasensitive Single Molecule Arrays
Real‐time monitoring of immune state and response to therapy can provide a means to
stratify patients and increase the number of responders who will benefit from approved and …
stratify patients and increase the number of responders who will benefit from approved and …
Tumor Biomarker In‐Solution Quantification, Standard Production, and Multiplex Detection
NC Japp, JJ Souchek, AR Sasson… - Journal of …, 2021 - Wiley Online Library
The diagnosis and monitoring of cancer have been facilitated by discovering tumor
“biomarkers” and methods to detect their presence. Yet, for certain cancers, we still lack …
“biomarkers” and methods to detect their presence. Yet, for certain cancers, we still lack …