Recent advances in the synthesis, functionalization and biomedical applications of hydroxyapatite: a review
Hydroxyapatite (HA) is a member of the Ca apatite family. It resembles natural bone in both
structure and chemical composition. HA, owing to its bioactive and biocompatible properties …
structure and chemical composition. HA, owing to its bioactive and biocompatible properties …
Nanophase hydroxyapatite as a biomaterial in advanced hard tissue engineering: a review
SM Zakaria, SH Sharif Zein, MR Othman… - … Engineering Part B …, 2013 - liebertpub.com
Hydroxyapatite is a biocompatible material that is extensively used in the replacement and
regeneration of bone material. In nature, nanostructured hydroxyapatite is the main …
regeneration of bone material. In nature, nanostructured hydroxyapatite is the main …
Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner
Engineering a pro-regenerative immune response following scaffold implantation is integral
to functional tissue regeneration. The immune response to implanted biomaterials is …
to functional tissue regeneration. The immune response to implanted biomaterials is …
3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration
FE Freeman, P Pitacco, LHA van Dommelen… - Science …, 2020 - science.org
Therapeutic growth factor delivery typically requires supraphysiological dosages, which can
cause undesirable off-target effects. The aim of this study was to 3D bioprint implants …
cause undesirable off-target effects. The aim of this study was to 3D bioprint implants …
Intercalated chitosan/hydroxyapatite nanocomposites: Promising materials for bone tissue engineering applications
Preparation and characterization of chitosan/hydroxyapatite (CS/HA) nanocomposites
displaying an intercalated structure is reported. Hydroxyapatite was synthesized through sol …
displaying an intercalated structure is reported. Hydroxyapatite was synthesized through sol …
The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation
The extent of regeneration following biomaterial implantation is dependent on the
microenvironment surrounding the implant. Since implant composition can have a profound …
microenvironment surrounding the implant. Since implant composition can have a profound …
Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues
The regeneration of complex tissues and organs remains a major clinical challenge. With a
view towards bioprinting such tissues, we developed a new class of pore-forming bioink to …
view towards bioprinting such tissues, we developed a new class of pore-forming bioink to …
[HTML][HTML] Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing
Angiogenesis is critical for successful bone repair, and interestingly, miR-210 and miR-16
possess counter-active targets involved in both angiogenesis and osteogenesis: miR-210 …
possess counter-active targets involved in both angiogenesis and osteogenesis: miR-210 …
A multifunctional scaffold for bone infection treatment by delivery of microRNA therapeutics combined with antimicrobial nanoparticles
JM Sadowska, RN Power, KJ Genoud… - Advanced …, 2024 - Wiley Online Library
Treating bone infections and ensuring bone repair is one of the greatest global challenges
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
Preparation and characterisation of nanophase Sr, Mg, and Zn substituted hydroxyapatite by aqueous precipitation
Hydroxyapatite (HA) substituted with 2 mol% Sr, 10 mol% Mg, and 2 mol% Zn were
precipitated under identical alkaline conditions (pH 11) at 20° C from an aqueous solution …
precipitated under identical alkaline conditions (pH 11) at 20° C from an aqueous solution …