Transcutaneous spinal cord stimulation and motor responses in individuals with spinal cord injury: A methodological review

C Taylor, C McHugh, D Mockler, C Minogue… - PLoS …, 2021 - journals.plos.org
Background Transcutaneous spinal cord stimulation (tSCS) is a non-invasive modality in
which electrodes can stimulate spinal circuitries and facilitate a motor response. This review …

Recent progress and challenges in the treatment of spinal cord injury

T Tian, S Zhang, M Yang - Protein & cell, 2023 - academic.oup.com
Spinal cord injury (SCI) disrupts the structural and functional connectivity between the higher
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …

Transcutaneous spinal cord stimulation restores hand and arm function after spinal cord injury

F Inanici, LN Brighton, S Samejima… - … on Neural Systems …, 2021 - ieeexplore.ieee.org
Paralysis of the upper extremity severely restricts independence and quality of life after
spinal cord injury. Regaining control of hand and arm movements is the highest treatment …

Noninvasive spinal stimulation safely enables upright posture in children with spinal cord injury

A Keller, G Singh, JH Sommerfeld, M King… - Nature …, 2021 - nature.com
In children with spinal cord injury (SCI), scoliosis due to trunk muscle paralysis frequently
requires surgical treatment. Transcutaneous spinal stimulation enables trunk stability in …

Non-invasive spinal cord electrical stimulation for arm and hand function in chronic tetraplegia: a safety and efficacy trial

C Moritz, EC Field-Fote, C Tefertiller, I van Nes… - Nature medicine, 2024 - nature.com
Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

Trans-spinal electrical stimulation therapy for functional rehabilitation after spinal cord injury

MA Rahman, NS Tharu, SM Gustin, YP Zheng… - Journal of clinical …, 2022 - mdpi.com
Spinal cord injury (SCI) is one of the most debilitating injuries in the world. Complications
after SCI, such as respiratory issues, bowel/bladder incontinency, pressure ulcers …

Spinal electrical stimulation to improve sympathetic autonomic functions needed for movement and exercise after spinal cord injury: a scoping clinical review

S Flett, J Garcia, KC Cowley - Journal of Neurophysiology, 2022 - journals.physiology.org
Spinal cord injury (SCI) results in sensory, motor, and autonomic dysfunction. Obesity,
cardiovascular disease, and metabolic disease are highly prevalent after SCI. Although …

Multisite Hebbian plasticity restores function in humans with spinal cord injury

HJ Jo, E Kizziar, S Sangari, D Chen… - Annals of …, 2023 - Wiley Online Library
Objective Spinal cord injury (SCI) damages synaptic connections between corticospinal
axons and motoneurons of many muscles, resulting in devastating paralysis. We …

Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

[HTML][HTML] Selectivity and excitability of upper-limb muscle activation during cervical transcutaneous spinal cord stimulation in humans

RM de Freitas, A Sasaki, DG Sayenko… - Journal of Applied …, 2021 - journals.physiology.org
Cervical transcutaneous spinal cord stimulation (tSCS) efficacy for rehabilitation of upper-
limb motor function was suggested to depend on recruitment of Ia afferents. However …