Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …

Successful cytosolic delivery of nanomaterials is becoming more and more important, given
the increase in intracellular applications of quantum dots, gold nanoparticles, liposomal drug …

The ultimate goal of drug delivery research is to help patients by developing clinically useful
formulations. During the last several decades controlled drug delivery technology has …

More than 40 nanomedicines are already in routine clinical use with a growing number
following in preclinical and clinical development. The therapeutic objectives are often …

At the time of the first issue of the Journal of Controlled Release (JCR), polymeric drugs,
polymer–drug and protein conjugates and block copolymer micelles carrying bound drugs …

Synthetic subunit vaccines need to induce CD8+ cytotoxic T cell (CTL) responses for
effective vaccination against intracellular pathogens. Most subunit vaccines primarily …

The development of safe, efficient and controllable gene-delivery vectors has become a
bottleneck to human gene therapy. Synthetic polymeric vectors, although safer than viral …

In the field of nanomedicine, ample attention has been paid to the development of
nanocarriers for the intracellular delivery of therapeutic cargo, such as nucleic acids for gene …

Poly (amidoamine) s (PAAs) are a family of synthetic polymers obtained by stepwise
polyaddition of prim‐or sec‐amines to bisacrylamides. Nearly all conceivable …

To improve the encapsulation efficiency and oral bioavailability of vincristine sulfate (VCR),
novel self-assembled dextran sulphate-PLGA hybrid nanoparticles (DPNs) were …