Purpose Potentially inappropriate medication (PIM) use causes preventable adverse drug
reactions in older patients. Several assessment tools have been published to identify and …

BACKGROUND: Osteoarthritis (OA) is the most common cause of disability in older adults,
and although analgesic use can be helpful, it can also result in adverse drug events …

Background There is a paucity of literature about the adverse events associated with
Therapeutic Dry Needling (TDN). Much of the literature surrounding adverse events …

Objective We aimed to assess the safety of topical non-steroidal anti-inflammatory drugs
(NSAIDs) in the management of osteoarthritis (OA) in a systematic review and meta-analysis …

Sarcopenia is characterized by reduced skeletal muscle mass and strength in older
individuals. It is one of the leading cause of physical limitation in older adults, and …

Some say that all diseases begin in the gut. Interestingly, this concept is actually quite old,
since it is attributed to the Ancient Greek physician Hippocrates, who proposed the …

Inflammation is the core contributor in the pathogenesis of various acute and chronic illness
including appendicitis, bronchitis, arthritis, cancer and neurological diseases. NSAIDs …

Probenecid is used to treat gout and hyperuricemia as well as increase plasma levels of
antiviral drugs and antibiotics. In vivo, probenecid mainly inhibits the renal SLC22 organic …

Osteoarthritis (OA) is the most common cause of disability worldwide among the elderly.
Alarmingly, the incidence of OA in individuals less than 40 years of age is rising, likely due to …

The subcellular mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) induce
apoptosis in gastric cancer and normal mucosal cells is elusive because of the diverse …