Oxidative stress has been considered as a major hallmark for the pathogenesis and
development of type 2 diabetes mellitus (T2DM), but still it is debatable whether it is a mere …

The body of evidence from the past three decades demonstrates that oxidative stress can be
involved in several diseases. This study aims to summarise the current state of knowledge …

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Pancreatic β-cell dysfunction plays an important role in the pathogenesis of both type 1 and
type 2 diabetes. Insulin, which is produced in β-cells, is a critical regulator of metabolism …

Type 2 diabetes (T2DM) commonly arises from islet β cell failure and insulin resistance.
Here, we examined the sensitivity of key islet-enriched transcription factors to oxidative …

Gallic acid is a trihydroxybenzoic acid of plant metabolites widely spread throughout the
plant kingdom. It has characteristics of the strong antioxidant and free radical scavenging …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Type 2 diabetes is the most prevalent and serious metabolic disease all over the world, and
its hallmarks are pancreatic β‐cell dysfunction and insulin resistance. Under diabetic …

This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological …

Glucotoxicity, lipotoxicity, and glucolipotoxicity are secondary phenomena that are proposed
to play a role in all forms of type 2 diabetes. The underlying concept is that once the primary …