Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel

AJ Taurozzi, PL Rüther, I Patramanis, C Koenig… - Nature …, 2024 - nature.com
In temperate and subtropical regions, ancient proteins are reported to survive up to about 2
million years, far beyond the known limits of ancient DNA preservation in the same areas …

Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets—Recent Insights at Molecular and Cellular Level

W Poller, S Sahoo, R Hajjar, U Landmesser… - Cells, 2023 - mdpi.com
While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …

Automated high-throughput biological sex identification from archeological human dental enamel using targeted proteomics

C Koenig, P Bortel, RS Paterson, B Rendl… - Journal of Proteome …, 2024 - ACS Publications
Biological sex is key information for archeological and forensic studies, which can be
determined by proteomics. However, the lack of a standardized approach for fast and …

Sex-biased sampling may influence Homo naledi tooth size variation

LK Delezene, JE Scott, JD Irish, A Villaseñor… - Journal of Human …, 2024 - Elsevier
A frequent source of debate in paleoanthropology concerns the taxonomic unity of fossil
assemblages, with many hominin samples exhibiting elevated levels of variation that can be …

Paleoproteomics sheds light on million-year-old fossils

RS Paterson, PP Madupe, E Cappellini - Nature Reviews Molecular …, 2024 - nature.com
It is now well established that ancient proteins endure, and remain informative, much longer
than DNA. Accordingly, sequencing of ancient proteins is currently the only viable …

[HTML][HTML] East and Southeast Asian hominin dispersal and evolution: A review

R Sawafuji, T Tsutaya, N Takahata… - Quaternary Science …, 2024 - Elsevier
Abstract East and Southeast Asia have served as significant habitats for diverse hominins for
more than one million years. This has been demonstrated by numerous studies over the …

[HTML][HTML] Taxonomic revision of the SK 15 mandible based on bone and tooth structural organization

C Zanolli, JJ Hublin, O Kullmer, F Schrenk… - Journal of Human …, 2025 - Elsevier
The hominin mandible SK 15 was discovered in April 1949 in Swartkrans Member 2, dated
to∼ 1.4 Ma. Albeit distorted on the right side, the left and right corpus of SK 15 are relatively …

A reanalysis of strontium isotope ratios as indicators of dispersal in South African hominins

MI Hamilton, SR Copeland, SV Nelson - Journal of Human Evolution, 2024 - Elsevier
Dispersal patterns in primates have major implications for behavior and sociality but are
difficult to reconstruct for fossil species. This study applies novel strontium isotope …

Comparative Context of Hard‐Tissue Sexual Dimorphism in Early Hominins: Implications for Alpha Taxonomy

KL Balolia, B Wood - Evolutionary Anthropology: Issues, News …, 2025 - Wiley Online Library
Sexual dimorphism is one of the main factors confounding attempts to generate sound alpha
taxonomic hypotheses in the early hominin fossil record. To better understand how between …

Cleaning the Dead: Optimized decontamination enhances palaeoproteomic analyses of Pleistocene skeletal material

Z Fagernäs, V Villa Islas, G Troché, JP Buylaert… - bioRxiv, 2024 - biorxiv.org
The study of ancient proteins preserved in a range of archaeological, cultural heritage, and
palaeontological materials is increasingly contributing to our understanding of human …