[HTML][HTML] The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV

L Wang, B Vulesevic, ML Vigano, A As' sadiq, K Kang… - Vaccines, 2024 - mdpi.com
HIV causes intense polyclonal activation of B cells, resulting in increased numbers of
spontaneously antibody-secreting cells in the circulation and hypergammaglobulinemia. It is …

Effect of SARS-CoV-2 Breakthrough Infection on HIV Reservoirs and T-Cell Immune Recovery in 3-Dose Vaccinated People Living with HIV

MM Qu, B Song, BP Yang, Z Wang, M Yu, Y Zhang… - Viruses, 2023 - mdpi.com
People living with human immunodeficiency virus (PLWH) are a vulnerable population with
a higher risk of severe coronavirus disease 2019 (COVID-19); therefore, vaccination is …

Within-host evolution of SARS-CoV-2: how often are de novo mutations transmitted from symptomatic infections?

CS Korosec, LM Wahl, JM Heffernan - Virus Evolution, 2024 - academic.oup.com
Despite a relatively low mutation rate, the large number of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections has allowed for substantial genetic …

SARS-CoV-2 booster vaccine dose significantly extends humoral immune response half-life beyond the primary series

CS Korosec, DW Dick, IR Moyles, J Watmough - Scientific Reports, 2024 - nature.com
SARS-CoV-2 lipid nanoparticle mRNA vaccines continue to be administered as the
predominant prophylactic measure to reduce COVID-19 disease pathogenesis. Quantifying …

Utility of accessible SARS-CoV-2 specific immunoassays in vaccinated adults with a history of advanced HIV infection

L Ferrari, A Ruggiero, C Stefani, L Benedetti… - Scientific Reports, 2024 - nature.com
Abstract Accessible SARS-CoV-2-specific immunoassays may inform clinical management
in people with HIV, particularly in case of persisting immunodysfunction. We prospectively …

[HTML][HTML] COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China

Y Li, Y Lin, Y Yi, N Zhu, X Cui, X Li - Vaccines, 2024 - mdpi.com
Objectives: Accumulating evidence has confirmed the efficacy and safety of COVID-19
vaccines against SARS-CoV-2 infection. However, the effect of COVID-19 vaccination on …

Immunogenicity and safety of inactivated SARS‐CoV‐2 vaccines in people living with HIV: A longitudinal cohort study

J Li, L Nie, C Guo, Y Deng, Q Guo… - Journal of Medical …, 2023 - Wiley Online Library
To clarify the characteristics in immunogenicity and safety of inactivated SARS‐Cov‐2
vaccines among HIV‐infected individuals, a longitudinal cohort study was performed on HIV …

Increase in HIV reservoir and T cell immune response after CoronaVac vaccination in people living with HIV

X Peng, X Zhu, X Liu, Y Huang, B Zhu - Heliyon, 2024 - cell.com
Introduction CoronaVac, an inactivated vaccine developed by Sinovac Life Sciences, has
been widely used for protection against Coronavirus Disease 2019 (COVID-19). This study …

[HTML][HTML] SARS-CoV-2 mRNA vaccination and short-term changes in viral load and CD4/CD8 T-cell counts in people living with HIV

A Vergori, A Cozzi-Lepri, A Tavelli, V Mazzotta… - International Journal of …, 2024 - Elsevier
Objectives To investigate whether SARS-CoV-2 messenger RNA (mRNA) vaccination has
an impact on HIV-related viro-immunological parameters. Methods People with HIV (PWH) …

Effects of COVID-19 mRNA vaccination on HIV viremia and reservoir size

MC Duncan, FH Omondi, NN Kinloch, HR Lapointe… - AIDS, 2022 - journals.lww.com
Objective: The immunogenic nature of COVID-19 mRNA vaccines led to some initial concern
that these could stimulate the HIV reservoir. We analyzed changes in plasma HIV loads …