Advances in the development of cyclodextrin-based nanogels/microgels for biomedical applications: Drug delivery and beyond

F Topuz, T Uyar - Carbohydrate Polymers, 2022 - Elsevier
Nanogels/microgels are swollen cross-linked polymer networks with tunable
physicochemical properties and are commonly employed for the effective delivery of …

Covalent Organic Framework Nanobowls as Activatable Nanosensitizers for Tumor‐Specific and Ferroptosis‐Augmented Sonodynamic Therapy

S Zhang, S Xia, L Chen, Y Chen, J Zhou - Advanced Science, 2023 - Wiley Online Library
Covalent organic frameworks (COFs) have attracted increasing attention for biomedical
applications. COFs‐based nanosensitizers with uniform nanoscale morphology and tumor …

Interface Assembly of Polymer Networks on Metal–Organic Frameworks for the Engineering of Functional Nanoparticles

Y Tian, Z Gao, M Li, M Hu, J Hao, J Cui - Chemistry of Materials, 2023 - ACS Publications
We report a versatile approach for the engineering of functional polymer nanoparticles (NPs)
with tunable sizes, stiffness, and responsiveness via templating zeolitic imidazolate …

Engineering advanced nanomedicines against central nervous system diseases

S Shi, H Ren, Y Xie, M Yu, Y Chen, L Yang - Materials Today, 2023 - Elsevier
Despite the impressive strides in the research community, numerous obstacles pose marked
challenges in the treatment of central nervous system (CNS) disorders. The limitations of …

The effect of elasticity of gelatin nanoparticles on the interaction with macrophages

M Yildirim, AV Weiss, M Schneider - Pharmaceutics, 2023 - mdpi.com
Gelatin is a biocompatible, biodegradable, cheap, and nontoxic material, which is already
used for pharmaceutical applications. Nanoparticles from gelatin (GNPs) are considered a …

Gadolinium (III)‐chelated deformable mesoporous organosilica nanoparticles as magnetic resonance imaging contrast agent

X Chen, S Teng, J Li, X Qiao, W Zhao, Z Xue… - Advanced …, 2023 - Wiley Online Library
Magnetic resonance imaging (MRI) contrast agents, such as Magnevist (Gd‐DTPA), are
routinely used for detecting tumors at an early stage. However, the rapid clearance by the …

Stiffness‐Transformable Nanoplatforms Responsive to the Tumor Microenvironment for Enhanced Tumor Therapeutic Efficacy

J Tao, Y Tian, D Chen, W Lu, K Chen, C Xu… - Angewandte …, 2023 - Wiley Online Library
Herein, we report, for the first time, a unique stiffness‐transformable manganese oxide
hybridized mesoporous organosilica nanoplatform (MMON) for enhancing tumor therapeutic …

Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging

Y Konishi, M Minoshima, K Fujihara… - Angewandte …, 2023 - Wiley Online Library
Abstract 19F magnetic resonance imaging (MRI) is a powerful molecular imaging technique
that enables high‐resolution imaging of deep tissues without background signal …

Closed-loop theranostic microgels for immune microenvironment modulation and microbiota remodeling in ulcerative colitis

Z Jin, Y Zhang, H Hu, Q Li, L Zhang, K Zhao, W Liu, L Li… - Biomaterials, 2025 - Elsevier
Inflammatory bowel disease (IBD) is characterized by the upregulation of reactive oxygen
species (ROS) and dysfunction of gut immune system, and microbiota. The conventional …

Transformative Materials for Interfacial Drug Delivery

P Desai, A Dasgupta, AM Sofias, Q Peña… - Advanced …, 2023 - Wiley Online Library
Drug delivery systems (DDS) are designed to temporally and spatially control drug
availability and activity. They assist in improving the balance between on‐target therapeutic …