Advances in the development of cyclodextrin-based nanogels/microgels for biomedical applications: Drug delivery and beyond
Nanogels/microgels are swollen cross-linked polymer networks with tunable
physicochemical properties and are commonly employed for the effective delivery of …
physicochemical properties and are commonly employed for the effective delivery of …
Covalent Organic Framework Nanobowls as Activatable Nanosensitizers for Tumor‐Specific and Ferroptosis‐Augmented Sonodynamic Therapy
Covalent organic frameworks (COFs) have attracted increasing attention for biomedical
applications. COFs‐based nanosensitizers with uniform nanoscale morphology and tumor …
applications. COFs‐based nanosensitizers with uniform nanoscale morphology and tumor …
Interface Assembly of Polymer Networks on Metal–Organic Frameworks for the Engineering of Functional Nanoparticles
We report a versatile approach for the engineering of functional polymer nanoparticles (NPs)
with tunable sizes, stiffness, and responsiveness via templating zeolitic imidazolate …
with tunable sizes, stiffness, and responsiveness via templating zeolitic imidazolate …
Engineering advanced nanomedicines against central nervous system diseases
S Shi, H Ren, Y Xie, M Yu, Y Chen, L Yang - Materials Today, 2023 - Elsevier
Despite the impressive strides in the research community, numerous obstacles pose marked
challenges in the treatment of central nervous system (CNS) disorders. The limitations of …
challenges in the treatment of central nervous system (CNS) disorders. The limitations of …
The effect of elasticity of gelatin nanoparticles on the interaction with macrophages
M Yildirim, AV Weiss, M Schneider - Pharmaceutics, 2023 - mdpi.com
Gelatin is a biocompatible, biodegradable, cheap, and nontoxic material, which is already
used for pharmaceutical applications. Nanoparticles from gelatin (GNPs) are considered a …
used for pharmaceutical applications. Nanoparticles from gelatin (GNPs) are considered a …
Gadolinium (III)‐chelated deformable mesoporous organosilica nanoparticles as magnetic resonance imaging contrast agent
Magnetic resonance imaging (MRI) contrast agents, such as Magnevist (Gd‐DTPA), are
routinely used for detecting tumors at an early stage. However, the rapid clearance by the …
routinely used for detecting tumors at an early stage. However, the rapid clearance by the …
Stiffness‐Transformable Nanoplatforms Responsive to the Tumor Microenvironment for Enhanced Tumor Therapeutic Efficacy
J Tao, Y Tian, D Chen, W Lu, K Chen, C Xu… - Angewandte …, 2023 - Wiley Online Library
Herein, we report, for the first time, a unique stiffness‐transformable manganese oxide
hybridized mesoporous organosilica nanoplatform (MMON) for enhancing tumor therapeutic …
hybridized mesoporous organosilica nanoplatform (MMON) for enhancing tumor therapeutic …
Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging
Y Konishi, M Minoshima, K Fujihara… - Angewandte …, 2023 - Wiley Online Library
Abstract 19F magnetic resonance imaging (MRI) is a powerful molecular imaging technique
that enables high‐resolution imaging of deep tissues without background signal …
that enables high‐resolution imaging of deep tissues without background signal …
Closed-loop theranostic microgels for immune microenvironment modulation and microbiota remodeling in ulcerative colitis
Z Jin, Y Zhang, H Hu, Q Li, L Zhang, K Zhao, W Liu, L Li… - Biomaterials, 2025 - Elsevier
Inflammatory bowel disease (IBD) is characterized by the upregulation of reactive oxygen
species (ROS) and dysfunction of gut immune system, and microbiota. The conventional …
species (ROS) and dysfunction of gut immune system, and microbiota. The conventional …
Transformative Materials for Interfacial Drug Delivery
Drug delivery systems (DDS) are designed to temporally and spatially control drug
availability and activity. They assist in improving the balance between on‐target therapeutic …
availability and activity. They assist in improving the balance between on‐target therapeutic …