Advances in the knowledge of the underlying airway remodeling mechanisms in chronic rhinosinusitis based on the endotypes: a review

K Lee, J Tai, SH Lee, TH Kim - International journal of molecular sciences, 2021 - mdpi.com
Chronic rhinosinusitis (CRS) is a chronic inflammatory condition of the nasal and paranasal
sinus mucosa that affects up to 10% of the population worldwide. CRS is the most …

Nasal polyposis: insights in epithelial-mesenchymal transition and differentiation of polyp mesenchymal stem cells

E Chiarella, N Lombardo, N Lobello, A Aloisio… - International journal of …, 2020 - mdpi.com
Chronic rhinosinusitis is a common inflammatory disease of paranasal sinuses, which
causes rhinorrhea, nasal congestion, and hyposmia. The genetic predisposition or the …

[HTML][HTML] Case Report: Successful use of phage therapy in refractory MRSA chronic rhinosinusitis

JM Rodriguez, BA Woodworth, J Fackler… - International Journal of …, 2022 - Elsevier
Case Report: successful use of phage therapy in refractory MRSA chronic rhinosinusitis -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Help Search …

Perspectives in therapy of chronic rhinosinusitis

J Brzost, K Czerwaty, K Dżaman, N Ludwig… - Diagnostics, 2022 - mdpi.com
The recent classification of chronic rhinosinusitis (CRS) focusses on investigating underlying
immunopathophysiological mechanisms. Primary CRS is subdivided based on endotype …

Chinese central compartment atopic disease: the clinical characteristics and cellular endotypes based on whole-slide imaging

W Kong, Q Wu, Y Chen, Y Ren, W Wang… - Journal of Asthma …, 2022 - Taylor & Francis
Purpose Histopathologic characterizations of central compartment atopic disease (CCAD)
by whole-slide imaging remains lacking. We aim to study clinical presentations and cellular …

Clinical assessment of chronic rhinosinusitis

C Hopkins, SE Lee, L Klimek, ZM Soler - The Journal of Allergy and Clinical …, 2022 - Elsevier
Chronic rhinosinusitis (CRS) is a common disease that affects> 10% of the adult population
in Europe and the United States. It has been delineated phenotypically into CRS without …

[HTML][HTML] LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species

S Zhang, A Lazrak, D Skinner, HM Thompson… - Redox Biology, 2021 - Elsevier
Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB)
and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a …

Elevated ALCAM expression associated with endotypes and postoperative recurrence in chronic rhinosinusitis with nasal polyps

H Zhang, S Xie, R Fan, F Wang, Z Xie… - Journal of inflammation …, 2022 - Taylor & Francis
Background Chronic rhinosinusitis with polyps (CRSwNP) is characterized by high
heterogeneity and postoperative recurrence rate. This study aimed to explore the clinical …

Monoclonal antibodies and airway diseases

A Lyly, A Laulajainen-Hongisto, P Gevaert… - International Journal of …, 2020 - mdpi.com
Monoclonal antibodies, biologics, are a relatively new treatment option for severe chronic
airway diseases, asthma, allergic rhinitis, and chronic rhinosinusitis (CRS). In this review, we …

Hormonal effects on asthma, rhinitis, and eczema

N Weare-Regales, SE Chiarella, JC Cardet… - The Journal of Allergy …, 2022 - Elsevier
Hormones significantly influence the pathogenesis of asthma, rhinitis, and eczema. This
review aims to summarize relevant clinical considerations for practicing allergists and …