Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …

Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), remains the
leading cause of death worldwide from a single infectious pathogen. Mtb is a paradigmatic …

The tripeptide glutathione plays important roles in many cell processes, including
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …

Low molecular weight (LMW) thiols contain reducing sulfhydryl groups that are important for
maintaining antioxidant defense in the cell. Aside from the traditional roles of LMW thiols as …

Background Liver injury is a common complication of anti-tuberculosis therapy. N-
acetylcysteine (NAC) used in patients with paracetamol toxicity with limited evidence of …

Given that infection with Mycobacterium tuberculosis (Mtb) is the leading cause of death
amongst individuals living with HIV, understanding the complex mechanisms by which Mtb …

Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Tuberculosis (TB) has been the most life-threatening contagious disease caused by
pathogenic mycobacterium tuberculosis. The World Health Organization (WHO) report, 2020 …

Mycobacterium tuberculosis (M. tb) has been historically and is currently a threat to global
public health. First-line antibiotics have been effective but proven to be burdensome as they …

Tuberculosis (TB) is a serious infectious disease caused by the pathogen Mycobacterium
tuberculosis (Mtb). The current therapy consists of a combination of antibiotics over the …