Bursting microbubbles: How nanobubble contrast agents can enable the future of medical ultrasound molecular imaging and image-guided therapy
The field of medical ultrasound has undergone a significant evolution since the development
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …
In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications
G Lajoinie, I De Cock, CC Coussios, I Lentacker… - …, 2016 - pubs.aip.org
Besides their use as contrast agents for ultrasound imaging, microbubbles are increasingly
studied for a wide range of therapeutic applications. In particular, their ability to enhance the …
studied for a wide range of therapeutic applications. In particular, their ability to enhance the …
Nonlinear dynamics of acoustic bubbles excited by their pressure-dependent subharmonic resonance frequency: influence of the pressure amplitude, frequency …
Nonlinear behavior of bubbles, and most importantly 1 2 1 2-order subharmonics (SH), are
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …
Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …
[HTML][HTML] An optical and acoustic investigation of microbubble cavitation in small channels under therapeutic ultrasound conditions
Therapeutic focused ultrasound in combination with encapsulated microbubbles is being
widely investigated for its ability to elicit bioeffects in the microvasculature, such as transient …
widely investigated for its ability to elicit bioeffects in the microvasculature, such as transient …
[HTML][HTML] A simple method to analyze the super-harmonic and ultra-harmonic behavior of the acoustically excited bubble oscillator
The bubble oscillator is a highly nonlinear system, which makes it difficult to generate a
comprehensive understanding of its oscillatory behavior. One method used to investigate …
comprehensive understanding of its oscillatory behavior. One method used to investigate …
Microbubble Composition and Preparation for High-Frequency Contrast-Enhanced Ultrasound Imaging: In Vitro and In Vivo Evaluation
Although high-frequency ultrasound imaging is gaining attention in various applications,
hardly any ultrasound contrast agents (UCAs) dedicated to such frequencies (> 15 MHz) are …
hardly any ultrasound contrast agents (UCAs) dedicated to such frequencies (> 15 MHz) are …
Effect of pulse shaping on subharmonic aided pressure estimation in vitro and in vivo
I Gupta, J Eisenbrey, M Stanczak… - … of Ultrasound in …, 2017 - Wiley Online Library
Objectives Subharmonic imaging (SHI) is a technique that uses the nonlinear oscillations of
microbubbles when exposed to ultrasound at high pressures transmitting at the fundamental …
microbubbles when exposed to ultrasound at high pressures transmitting at the fundamental …
[HTML][HTML] Experimental investigation on the effect of concentration on the resonance frequency of lipid coated ultrasonically excited microbubbles
This study presents an experimental investigation of the influence of MB concentration on
the resonance frequency of lipid-coated microbubbles (MBs). Expanding on theoretical …
the resonance frequency of lipid-coated microbubbles (MBs). Expanding on theoretical …
Novel anti-VEGFR2 antibody-conjugated nanobubbles for targeted ultrasound molecular imaging in a rabbit VX2 hepatic tumor model
H Yu, S Zheng, C Wang, J Xing, L Li - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Nanobubbles (NBs), as ultrasound contrast agents, possess the potential for clinical
applications in targeted ultrasound molecular imaging due to their small diameters and the …
applications in targeted ultrasound molecular imaging due to their small diameters and the …