Efficient preparation of unsymmetrical disulfides by nickel-catalyzed reductive coupling strategy

F Wang, Y Chen, W Rao, L Ackermann… - Nature …, 2022 - nature.com
Disulfides are widely found in natural products and find a wide range of applications in life
sciences, materials chemistry and other fields. The preparation of disulfides mainly rely on …

An overview of recent advances in the synthesis of organic unsymmetrical disulfides

CL Ong, S Titinchi, JC Juan… - Helvetica Chimica …, 2021 - Wiley Online Library
Organic unsymmetrical disulfides have been extensively applied in various academic and
industrial fields including intermediates in organic synthesis, agriculture, and food science …

Photo-induced decarboxylative CS bond formation to access sterically hindered unsymmetric S-alkyl thiosulfonates and SS-alkyl thiosulfonates

Y Guo, G Lin, M Zhang, J Xu, Q Song - Nature Communications, 2024 - nature.com
Due to the high reactivity and versatility of benzenesulfonothioates, significant
advancements have been made in constructing CS bonds. However, there are certain …

Copper (I)‐Catalyzed Asymmetric Interrupted Kinugasa Reaction: Synthesis of α‐Thiofunctional Chiral β‐Lactams

J Qi, F Wei, S Huang, CH Tung, Z Xu - Angewandte Chemie, 2021 - Wiley Online Library
A copper (I)‐catalyzed asymmetric, three‐component interrupted Kinugasa reaction has
been developed. Diverse chiral sulfur‐containing chiral β‐lactams with two consecutive …

Access to polysulfides through photocatalyzed dithiosulfonylation

X Ren, Q Ke, Y Zhou, J Jiao, G Li, S Cao… - Angewandte …, 2023 - Wiley Online Library
In this study, we outline a general method for photocatalyzed difunctionalization of alkenes,
a diene, alkynes, 1, 3‐enynes, and [1.1. 1] propellane using dithiosulfonate reagents (ArSO2 …

Unsymmetrical polysulfidation via designed bilateral disulfurating reagents

J Xue, X Jiang - Nature Communications, 2020 - nature.com
Sulfur-sulfur motifs widely occur in vital function and drug design, which yearns for
polysulfide construction in an efficient manner. However, it is a great challenge to install …

Radical substitution provides a unique route to disulfides

Z Wu, DA Pratt - Journal of the American Chemical Society, 2020 - ACS Publications
Radical substitution on tetrasulfides is demonstrated to be a highly effective means to
prepare unsymmetric disulfides. Alkyl and aryl radicals generated thermally or …

A Divergent Strategy for Site‐Selective Radical Disulfuration of Carboxylic Acids with Trisulfide‐1, 1‐Dioxides

Z Wu, DA Pratt - Angewandte Chemie, 2021 - Wiley Online Library
The direct conversion of carboxylic acids into disulfides is described. The approach employs
oxidative photocatalysis for base‐promoted decarboxylation of the substrate, which yields …

N‐(Morpholine‐4‐dithio)phthalimide: A Shelf‐Stable, Bilateral Platform Molecule Enabling Access to Diverse Unsymmetrical Disulfides**

H Asanuma, K Kanemoto, T Watanabe… - Angewandte …, 2023 - Wiley Online Library
Synthetic methods for unsymmetrical disulfides are greatly needed owing to their
applications in drug discovery, linker chemistry, and materials sciences. In this study, a new …

Synthesis of Alkynyl Sulfides: Alkynyl Trifluoromethyl Sulfides and Thiocyanates

C Zeng, Z Yuan, Y Jiao, L Peng… - European Journal of …, 2023 - Wiley Online Library
Sulfur‐containing alkynes, are important starting materials and intermediates in organic
reactions. Some of sulfur‐containing alkynes display interesting bioactivities and are …