Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Nonalcoholic fatty liver disease (NAFLD) is prevalent in patients with obesity or type 2
diabetes. Nonalcoholic steatohepatitis (NASH), encompassing steatosis with inflammation …

OBJECTIVE Persons with diabetes have accelerated muscle loss compared with their
counterparts. The relationship of hyperglycemia per se to declines in muscle function has …

Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in
women of reproductive age. Its heterogeneous clinical presentation is characterized by …

Insulin resistance precedes and predicts the onset of type 2 diabetes (T2D) in susceptible
humans, underscoring its important role in the complex pathogenesis of this disease. Insulin …

Sarcopenia is defined as age‐associated loss of muscle mass and function, and is
frequently accompanied by diabetes mellitus (DM) in older adults. Some of the mechanisms …

We summarize the existing literature data concerning the involvement of skeletal muscle
(SM) in whole body glucose homeostasis and the contribution of SM insulin resistance (IR) …

Multiple organs contribute to the development of peripheral insulin resistance, with the major
contributors being skeletal muscle, liver, and adipose tissue. Because insulin resistance …