Asthma exacerbations occur across a wide spectrum of chronic severity; they contribute to
millions of emergency department (ED) visits in both children and adults every year …

Asthma is the most common chronic disease of childhood worldwide, and is responsible for
significant morbidity and mortality in children and young people (CYP). Given the inherent …

Background Asthma is the most common chronic disease of childhood and a major source
of childhood health burden worldwide. These burdens are particularly marked when …

BACKGROUND: The aim of these clinical standards is to aid the diagnosis and
management of asthma in low-resource settings in low-and middle-income countries …

Rationale Severe acute paediatric asthma may require treatment escalation beyond
systemic corticosteroids, inhaled bronchodilators and low-flow oxygen. Current large asthma …

OBJECTIVES: Children with status asthmaticus refractory to first-line therapies of systemic
corticosteroids and inhaled beta-agonists often receive additional treatments. Because there …

What is the most appropriate second-line intravenous bronchodilator treatment when a child
with a severe asthma attack is not responsive to initial inhaled therapy? The second-line …

Asthma is the most common chronic illness in children, with> 700,000 emergency
department (ED) visits each year. Asthma is a respiratory disease characterized by a …

Background Acute severe childhood asthma is an infrequent, but potentially life-threatening
emergency condition. There is a wide range of different approaches to this condition, with …

Multicentre research provides advantages over singlecentre research by maximising
available patient numbers while pooling varied expertise and resources available across …