Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

Osteoporosis is a common disorder, affecting hundreds of millions of people worldwide, and
characterized by decreased bone mineral density and increased fracture risk. Known …

Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative
effects, but their role in osteogenesis and the underlying mechanism are yet to be …

Biomarkers are essential tools in clinical research and practice. Useful biomarkers must
combine good measurability, validated association with biological processes or outcomes …

Osteoporosis is the consequence of altered bone metabolism resulting in the systemic
reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) …

Osteoporosis is a major concern worldwide and can be attributed to an imbalance between
osteoblastic bone formation and osteoclastic bone resorption due to the natural aging …

Background and aim The biological functions of non-coding RNAs (ncRNAs) have been
widely identified in many human diseases. In the present study, the relationship between …

Progression of breast cancer to metastatic bone disease is linked to deregulated expression
of the transcription factor Runx2. Therefore, our goal was to evaluate the potential for clinical …

MicroRNAs (miRNAs) are highly conserved noncoding RNAs of about 19-25 nucleotides.
Through specifically pairing with complementary sites in 3'untranslated regions (UTRs) of …

Over the last 15 years several biological markers of bone turnover have been developed
with increased specificity and sensitivity. In osteoporosis clinical studies, the IOF and IFCC …