Urban vs. rural factors that affect adult asthma
Y Jie, ZM Isa, X Jie, ZL Ju, NH Ismail - Reviews of Environmental …, 2013 - Springer
People in modern societies spend the vast majority of their time in indoor environments,
including homes, workplaces, schools, and public spaces. Hence, indoor environmental …
including homes, workplaces, schools, and public spaces. Hence, indoor environmental …
HIV fusion inhibitors
MI Qadir, SA Malik - Reviews in Medical Virology, 2010 - Wiley Online Library
Drugs based on amino acid sequence of Heptad Repeats of gp41 of HIV have been
explored in search of anti‐HIV drugs acting by inhibition of the gp41 6‐helix formation and …
explored in search of anti‐HIV drugs acting by inhibition of the gp41 6‐helix formation and …
Peptide-based inhibitors of the HIV envelope protein and other class I viral fusion proteins
I Steffen, S Pohlmann - Current pharmaceutical design, 2010 - ingentaconnect.com
Viruses need to deliver their genomic information into the host cell lumen to establish
productive infection. Enveloped viruses accomplish this task by fusing their membrane with …
productive infection. Enveloped viruses accomplish this task by fusing their membrane with …
HIV Type 1 Molecular Epidemiology in pol and gp41 Genes Among Naive Patients from Mato Grosso do Sul State, Central Western Brazil
AA da Silveira, LPV Cardoso… - AIDS research and …, 2012 - liebertpub.com
Abstract Antiretroviral naive patients (n= 49) were recruited in central western Brazil (Campo
Grande City/Mato Grosso do Sul State, located across the Bolivia and Paraguay borders) …
Grande City/Mato Grosso do Sul State, located across the Bolivia and Paraguay borders) …
Evaluation of primary resistance to HIV entry inhibitors among brazilian patients failing reverse transcriptase/protease inhibitors treatment reveal high prevalence of …
CS Alencar, AS Nishiya, S Ferreira… - AIDS research and …, 2010 - liebertpub.com
Entry inhibitor is a new class of drugs that target the viral envelope protein. This region is
variable; hence resistance to these drugs may be present before treatment. The aim of this …
variable; hence resistance to these drugs may be present before treatment. The aim of this …
High Level of Multidrug Resistance Mutations in HIV Type 1 pol Gene and Resistance-Associated Mutations to Enfuvirtide (T-20) among Antiretroviral-Experienced …
LPV Cardoso, MM de Araujo Stefani - AIDS research and human …, 2009 - liebertpub.com
HIV-1 resistance mutations to antiretroviral (ARV) drugs (nucleoside reverse transcriptase
inhibitors, NRTI; nonnucleoside reverse transcriptase inhibitors, NNRTI; and protease …
inhibitors, NRTI; nonnucleoside reverse transcriptase inhibitors, NNRTI; and protease …
Novel HIV-1 fusion inhibition peptides: designing the next generation of drugs
F Miyamoto, EN Kodama - Antiviral Chemistry and …, 2012 - journals.sagepub.com
The development of over 20 antiretroviral drugs has led to efficient and successful
suppression of HIV-1 replication. In addition to common viral targets, such as reverse …
suppression of HIV-1 replication. In addition to common viral targets, such as reverse …
Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design
K Izumi, K Kawaji, F Miyamoto, K Shimane… - The international journal …, 2013 - Elsevier
T-20 (enfuvirtide) resistance is caused by the N43D primary resistance mutation at its
presumed binding site at the N-terminal heptad repeat (N-HR) of gp41, accompanied by the …
presumed binding site at the N-terminal heptad repeat (N-HR) of gp41, accompanied by the …
high polymorphism rates in the HR1 and HR2 gp41 and presence of primary resistance-related mutations in HIV type 1 circulating in Brazil: possible impact on …
C Teixeira, D de Sá-Filho, W Alkmim… - AIDS research and …, 2010 - liebertpub.com
We analyzed the gp41 sequences of 80 HIV-infected enfuvirtide-naive individuals who were
eligible to receive this antiretroviral according to Brazilian guidelines. We analyzed the …
eligible to receive this antiretroviral according to Brazilian guidelines. We analyzed the …
Genotypic analysis of the gp41 HR1 region from HIV-1 isolates from enfuvirtide-treated and untreated patients
LS Pessoa, ALC Valadão, CM Abreu… - JAIDS Journal of …, 2011 - journals.lww.com
Objective: To evaluate the polymorphisms and resistance mutations in gp41 HR1 region of
HIV-1. Methods: The study included 28 HIV-positive patients undergoing enfuvirtide (ENF) …
HIV-1. Methods: The study included 28 HIV-positive patients undergoing enfuvirtide (ENF) …