A review of colorectal cancer in terms of epidemiology, risk factors, development, symptoms and diagnosis

T Sawicki, M Ruszkowska, A Danielewicz… - Cancers, 2021 - mdpi.com
Simple Summary According to the available data, colorectal cancer (CRC) is one of the most
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Gut microbiome, big data and machine learning to promote precision medicine for cancer

G Cammarota, G Ianiro, A Ahern, C Carbone… - Nature reviews …, 2020 - nature.com
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …

Influence of the gut microbiome, diet, and environment on risk of colorectal cancer

M Song, AT Chan, J Sun - Gastroenterology, 2020 - Elsevier
Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

The intestinal microbiota in colorectal cancer

H Tilg, TE Adolph, RR Gerner, AR Moschen - Cancer cell, 2018 - cell.com
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …

[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential

E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …

The oral microbiota in colorectal cancer is distinctive and predictive

B Flemer, RD Warren, MP Barrett, K Cisek, A Das… - Gut, 2018 - gut.bmj.com
Background and aims Microbiota alterations are linked with colorectal cancer (CRC) and
notably higher abundance of putative oral bacteria on colonic tumours. However, it is not …

Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers

Z Dai, OO Coker, G Nakatsu, WKK Wu, L Zhao, Z Chen… - Microbiome, 2018 - Springer
Background Alterations of gut microbiota are associated with colorectal cancer (CRC) in
different populations and several bacterial species were found to contribute to the …

A novel faecal Lachnoclostridium marker for the non-invasive diagnosis of colorectal adenoma and cancer

JQ Liang, T Li, G Nakatsu, YX Chen, TO Yau, E Chu… - Gut, 2020 - gut.bmj.com
Objective There is a need for early detection of colorectal cancer (CRC) at precancerous-
stage adenoma. Here, we identified novel faecal bacterial markers for diagnosing adenoma …