Hepatitis B virus research in South Africa

MB Maepa, A Ely, A Kramvis, K Bloom, K Naidoo… - Viruses, 2022 - mdpi.com
Despite being vaccine-preventable, hepatitis B virus (HBV) infection remains the seventh
leading cause of mortality in the world. In South Africa (SA), over 1.9 million people are …

Spacer Domain in Hepatitis B Virus Polymerase: Plugging a Hole or Performing a Role?

C Pley, J Lourenço, AL McNaughton… - Journal of …, 2022 - Am Soc Microbiol
Hepatitis B virus (HBV) polymerase is divided into terminal protein, spacer, reverse
transcriptase, and RNase domains. Spacer has previously been considered dispensable …

Estimating hepatitis B virus cccDNA persistence in chronic infection

KA Lythgoe, SF Lumley, L Pellis, JA McKeating… - Virus …, 2021 - academic.oup.com
Hepatitis B virus (HBV) infection is a major global health problem with over 240 million
infected individuals at risk of developing progressive liver disease and hepatocellular …

Cohort Profile: The National Institute for Health Research Health Informatics Collaborative: Hepatitis B Virus (NIHR HIC HBV) research dataset

T Wang, DA Smith, C Campbell… - International Journal …, 2023 - academic.oup.com
Chronic infection with hepatitis B virus (HBV) is a global health problem, resulting in an
estimated 887000 deaths worldwide in 2015. 1 Unlike deaths from other infections such as …

Management of bimaxillary protrusion

RK Rajandram, L Ponnuthurai… - Oral and …, 2023 - oralmaxsurgery.theclinics.com
Bimaxillary protrusion is a dentofacial deformity trait that can present in all different skeletal
patterns. Clinically, the trait is associated with the presence of a protrusive anterior …

Pan-genotypic probe-based enrichment to improve efficiency of Hepatitis B virus sequencing

SF Lumley, D Jennings, E Waddilove, A Trebes… - BioRxiv, 2023 - biorxiv.org
ABSTRACT Hepatitis B Virus (HBV) genome sequencing can be used to provide more
complete genetic information at the population and individual level to shed light on the …

Cohort Profile: National Institute for Health Research Health Informatics Collaborative: Hepatitis B Virus (NIHR HIC HBV) Research Dataset

T Wang, DA Smith, C Campbell, O Freeman… - medRxiv, 2021 - medrxiv.org
Abstract Purpose The National Institute for Health Research (NIHR) Health Informatics
Collaborative (HIC) was established to enable re-use of routinely collected clinical data …

Endemic HBV among hospital in-patients in Bangladesh, including evidence of occult infection

FR Chowdhury, AL McNaughton… - Journal of General …, 2021 - microbiologyresearch.org
Bangladesh is one of the top-ten most heavily burdened countries for viral hepatitis, with
hepatitis B (HBV) infections responsible for the majority of cases. Recombinant and occult …

Pool testing with dilution effects and heterogeneous priors

GQ Saraiva - Health Care Management Science, 2023 - Springer
The Dorfman pooled testing scheme is a process in which individual specimens (eg, blood,
urine, swabs, etc.) are pooled and tested together; if the merged sample tests positive for …

Spatial and Molecular Epidemiology of Hepatitis B Virus in the Democratic Republic of Congo

CE Morgan - 2024 - search.proquest.com
Hepatitis B virus (HBV) remains endemic in the WHO Africa region, despite an effective
vaccine. Evidence from Africa suggests transmission at household-and community-levels …