Bone fracture is a very common body injury. The healing process is physiologically complex,
involving both biological and mechanical aspects. Following a fracture, cell migration …

A review about design, manufacture, and mechanobiology of biodegradable scaffolds for
bone tissue engineering is given. First, fundamental aspects about bone tissue engineering …

Many biological tissues, such as wood and bone, are fiber composites with a hierarchical
structure. Their exceptional mechanical properties are believed to be due to a functional …

Fractures heal predominantly through the process of endochondral ossification. The classic
model of endochondral ossification holds that chondrocytes mature to hypertrophy, undergo …

Extracellular matrix can influence stem cell choices, such as self‐renewal, quiescence,
migration, proliferation, phenotype maintenance, differentiation, or apoptosis. Three aspects …

Many biochemical factors regulating progenitor cell differentiation have been examined in
detail; however, the role of the local mechanical environment on stem cell fate has only …

Craniofacial tissue engineering promises the regeneration or de novo formation of dental,
oral, and craniofacial structures lost to congenital anomalies, trauma, and diseases. Virtually …

It is becoming increasingly clear that mesenchymal stem cell (MSC) differentiation is
regulated by mechanical signals. Mechanical forces generated intrinsically within the cell in …

Research in bioprinting is booming due to its potential in addressing several manufacturing
challenges in regenerative medicine. However, there are still many hurdles to overcome to …

Mechanotransduction is the process by which physical forces are converted into
biochemical signals that are then integrated into cellular responses. It plays a crucial role in …