Orchard: building large cancer phylogenies using stochastic combinatorial search

E Kulman, R Kuang, Q Morris - PLOS Computational Biology, 2024 - journals.plos.org
Phylogenies depicting the evolutionary history of genetically heterogeneous subpopulations
of cells from the same cancer, ie, cancer phylogenies, offer valuable insights about cancer …

Evolutionary pressures shape soft tissue sarcoma development and radiotherapy response

E Blomain, S Soudi, A Somani, A Subramanian… - 2023 - researchsquare.com
Evolutionary pressures play a key role in tumorigenesis, progression, and response to
therapy. However, the selection pressures and subclonal dynamics of soft tissue sarcomas …

[PDF][PDF] Deconvolution of Genetic Heterogeneity in Glioblastoma

A Gillmor - 2024 - prism.ucalgary.ca
Glioblastoma, an aggressive brain tumor, exhibits substantial genetic heterogeneity that
contributes to functional variations and poor outcomes. To comprehensively understand this …

[PDF][PDF] EDUCATION, MIGRATION AND SUSTAINABILITY-HUMAN SOCIOECONOMIC DEVELOPMENT AND CHANGING TECHNOLOGICAL TRENDS

P Sharma - researchgate.net
Technological innovations earmark the trends witnessed today, driving various economic
statuses. The current trends driving the education, migration, and sustainability of the human …